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Prolonged Survival in a Patient with a Pancreatic Acinar Cell Carcinoma.
Ploquin, Anne; Baldini, Capucine; Vuagnat, Perrine; Makhloufi, Samira; Desauw, Christophe; Hebbar, Mohamed.
Afiliación
  • Ploquin A; Department of Medical Oncology, University Hospital, Lille, France.
  • Baldini C; Department of Medical Oncology, University Hospital, Lille, France.
  • Vuagnat P; Department of Medical Oncology, University Hospital, Lille, France.
  • Makhloufi S; Department of Medical Oncology, University Hospital, Lille, France.
  • Desauw C; Department of Medical Oncology, University Hospital, Lille, France.
  • Hebbar M; Department of Medical Oncology, University Hospital, Lille, France.
Case Rep Oncol ; 8(3): 447-50, 2015.
Article en En | MEDLINE | ID: mdl-26600777
Pancreatic acinar cell carcinoma (ACC) is a rare entity. Herein we present the case of a 50-year-old male patient with an unlimited mass on the pancreatic corpus and tail with peripancreatic effusion and multiple metastases in the liver and spleen. A liver biopsy showed a pancreatic ACC. The patient received 9 cycles of gemcitabine plus oxaliplatin (GEMOX regimen), which had to be stopped because of a persistent grade 2 neuropathy. A CT scan showed complete response after 14 years. At the age of 61 years, a localized prostatic cancer was diagnosed, treated by prostatectomy. The patient carried a BRCA2 mutation. None of the precedent case reports describe a chemosensibility to the GEMOX regimen. In spite of the lack of study in these patients, chemotherapy with oxaliplatin seems to be the most effective. Long survival can be expected.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Case Rep Oncol Año: 2015 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Case Rep Oncol Año: 2015 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Suiza