SDF1-CXCR4 signaling contributes to persistent pain and hypersensitivity via regulating excitability of primary nociceptive neurons: involvement of ERK-dependent Nav1.8 up-regulation.

Yang, Fei; Sun, Wei; Yang, Yan; Wang, Yan; Li, Chun-Li; Fu, Han; Wang, Xiao-Liang; Yang, Fan; He, Ting; Chen, Jun

Yang, Fei; Sun, Wei; Yang, Yan; Wang, Yan; Li, Chun-Li; Fu, Han; Wang, Xiao-Liang; Yang, Fan; He, Ting; Chen, Jun.

Afiliación

Yang F; Institute for Biomedical Sciences of Pain, Tangdu Hospital, The Fourth Military Medical University, #569 Xinsi Road, Baqiao, Xi'an, 710038, People's Republic of China.
Sun W; Institute for Biomedical Sciences of Pain, Tangdu Hospital, The Fourth Military Medical University, #569 Xinsi Road, Baqiao, Xi'an, 710038, People's Republic of China.
Yang Y; Key Laboratory of Brain Stress and Behavior, PLA, Xi'an, 710038, People's Republic of China.
Wang Y; Beijing Institute for Brain Disorders, Beijing, 100069, People's Republic of China.
Li CL; Institute for Biomedical Sciences of Pain, Tangdu Hospital, The Fourth Military Medical University, #569 Xinsi Road, Baqiao, Xi'an, 710038, People's Republic of China.
Fu H; Key Laboratory of Brain Stress and Behavior, PLA, Xi'an, 710038, People's Republic of China.
Wang XL; Institute for Biomedical Sciences of Pain, Tangdu Hospital, The Fourth Military Medical University, #569 Xinsi Road, Baqiao, Xi'an, 710038, People's Republic of China.
Yang F; Key Laboratory of Brain Stress and Behavior, PLA, Xi'an, 710038, People's Republic of China.
He T; Institute for Biomedical Sciences of Pain, Tangdu Hospital, The Fourth Military Medical University, #569 Xinsi Road, Baqiao, Xi'an, 710038, People's Republic of China.
Chen J; Key Laboratory of Brain Stress and Behavior, PLA, Xi'an, 710038, People's Republic of China.

J Neuroinflammation ; 12: 219, 2015 Nov 24.

Article en En | MEDLINE | ID: mdl-26597700

Asunto(s)

Quimiocina CXCL12/biosíntesis; Hiperalgesia/metabolismo; Sistema de Señalización de MAP Quinasas/fisiología; Canal de Sodio Activado por Voltaje NAV1.8/biosíntesis; Nociceptores/metabolismo; Receptores CXCR4/biosíntesis; Animales; Masculino; Neuronas/metabolismo; Dolor/metabolismo; Ratas; Ratas Sprague-Dawley; Regulación hacia Arriba/fisiología

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nociceptores / Receptores CXCR4 / Sistema de Señalización de MAP Quinasas / Quimiocina CXCL12 / Canal de Sodio Activado por Voltaje NAV1.8 / Hiperalgesia Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google