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Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.
Pobbati, Ajaybabu V; Han, Xiao; Hung, Alvin W; Weiguang, Seetoh; Huda, Nur; Chen, Guo-Ying; Kang, CongBao; Chia, Cheng San Brian; Luo, Xuelian; Hong, Wanjin; Poulsen, Anders.
Afiliación
  • Pobbati AV; Institute of Molecular and Cell Biology, A(∗)STAR, 61 Biopolis Drive, Singapore 138673, Singapore. Electronic address: ajaybabuvp@imcb.a-star.edu.sg.
  • Han X; Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China; Department of Pharmacology, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390, USA.
  • Hung AW; Experimental Therapeutics Centre, A(∗)STAR, 31 Biopolis Way, #3-01, Singapore 138669, Singapore.
  • Weiguang S; Experimental Therapeutics Centre, A(∗)STAR, 31 Biopolis Way, #3-01, Singapore 138669, Singapore.
  • Huda N; Experimental Therapeutics Centre, A(∗)STAR, 31 Biopolis Way, #3-01, Singapore 138669, Singapore.
  • Chen GY; Experimental Therapeutics Centre, A(∗)STAR, 31 Biopolis Way, #3-01, Singapore 138669, Singapore.
  • Kang C; Experimental Therapeutics Centre, A(∗)STAR, 31 Biopolis Way, #3-01, Singapore 138669, Singapore.
  • Chia CS; Experimental Therapeutics Centre, A(∗)STAR, 31 Biopolis Way, #3-01, Singapore 138669, Singapore.
  • Luo X; Department of Pharmacology, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390, USA. Electronic address: xuelian.luo@utsouthwestern.edu.
  • Hong W; Institute of Molecular and Cell Biology, A(∗)STAR, 61 Biopolis Drive, Singapore 138673, Singapore.
  • Poulsen A; Experimental Therapeutics Centre, A(∗)STAR, 31 Biopolis Way, #3-01, Singapore 138669, Singapore. Electronic address: apoulsen@etc.a-star.edu.sg.
Structure ; 23(11): 2076-86, 2015 Nov 03.
Article en En | MEDLINE | ID: mdl-26592798

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Antiinflamatorios no Esteroideos / Proteínas de Unión al ADN / Antineoplásicos Límite: Humans Idioma: En Revista: Structure Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Antiinflamatorios no Esteroideos / Proteínas de Unión al ADN / Antineoplásicos Límite: Humans Idioma: En Revista: Structure Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos