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Complete genome sequence of novel T7-like virus vB_KpnP_KpV289 with lytic activity against Klebsiella pneumoniae.
Volozhantsev, Nikolay V; Myakinina, Vera P; Popova, Anastasia V; Kislichkina, Angelina A; Komisarova, Ekaterina V; Knyazeva, Anastasia I; Krasilnikova, Valentina M; Fursova, Nadezhda K; Svetoch, Eduard A.
Afiliación
  • Volozhantsev NV; State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, 142279, Russian Federation. nikvol@obolensk.org.
  • Myakinina VP; State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, 142279, Russian Federation.
  • Popova AV; State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, 142279, Russian Federation.
  • Kislichkina AA; State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, 142279, Russian Federation.
  • Komisarova EV; State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, 142279, Russian Federation.
  • Knyazeva AI; State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, 142279, Russian Federation.
  • Krasilnikova VM; State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, 142279, Russian Federation.
  • Fursova NK; State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, 142279, Russian Federation.
  • Svetoch EA; State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, 142279, Russian Federation.
Arch Virol ; 161(2): 499-501, 2016 Feb.
Article en En | MEDLINE | ID: mdl-26577901
A novel bacteriophage, vB_KpnP_KpV289, lytic for hypermucoviscous strains of Klebsiella pneumoniae, was attributed to the family Podoviridae, subfamily Autographivirinae, genus T7likevirus based on transmission electron microscopy and genome analysis. The complete genome of the bacteriophage vB_KpnP_KpV289 consists of a linear double-stranded DNA of 41,054 bp including 179-bp direct-repeat sequences at the ends and 51 open reading frames (ORFs). The G+C content is 52.56 %. The phage was shown to lyse 15 out of 140 (10.7 %) K. pneumoniae strains belonged to the capsular types K-1, K-2, and K-57 and strains without a determined capsular type, including a hypermucoviscous strain of the novel sequence type ST-1554.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacteriólisis / ADN Viral / Genoma Viral / Podoviridae / Klebsiella pneumoniae Idioma: En Revista: Arch Virol Año: 2016 Tipo del documento: Article Pais de publicación: Austria

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacteriólisis / ADN Viral / Genoma Viral / Podoviridae / Klebsiella pneumoniae Idioma: En Revista: Arch Virol Año: 2016 Tipo del documento: Article Pais de publicación: Austria