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A new role for an old drug: Ambroxol triggers lysosomal exocytosis via pH-dependent Ca²âº release from acidic Ca²âº stores.
Fois, Giorgio; Hobi, Nina; Felder, Edward; Ziegler, Andreas; Miklavc, Pika; Walther, Paul; Radermacher, Peter; Haller, Thomas; Dietl, Paul.
Afiliación
  • Fois G; Institute of General Physiology, University of Ulm, Albert-Einstein Allee 11, 89081 Ulm, Germany. Electronic address: giorgio.fois@uni-ulm.de.
  • Hobi N; Institute of General Physiology, University of Ulm, Albert-Einstein Allee 11, 89081 Ulm, Germany; Department of Physiology and Medical Physics, Division of Physiology, Medical University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria. Electronic address: nina.hobi@uni-ulm.de.
  • Felder E; Institute of General Physiology, University of Ulm, Albert-Einstein Allee 11, 89081 Ulm, Germany. Electronic address: edward.felder@uni-ulm.de.
  • Ziegler A; Z. E. Elektronenmikroskopie, Universität Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany. Electronic address: andreas.ziegler@uni-ulm.de.
  • Miklavc P; Institute of General Physiology, University of Ulm, Albert-Einstein Allee 11, 89081 Ulm, Germany. Electronic address: pika.miklavc@uni-ulm.de.
  • Walther P; Z. E. Elektronenmikroskopie, Universität Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany. Electronic address: paul.walther@uni-ulm.de.
  • Radermacher P; Institut für Anästhesiologische Pathophysiologie und Verfahrensentwicklung, University of Ulm, Albert-Einstein Allee 11, 89081 Ulm, Germany. Electronic address: peter.radermacher@uni-ulm.de.
  • Haller T; Department of Physiology and Medical Physics, Division of Physiology, Medical University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria. Electronic address: thomas.haller@i-med.ac.at.
  • Dietl P; Institute of General Physiology, University of Ulm, Albert-Einstein Allee 11, 89081 Ulm, Germany. Electronic address: paul.dietl@uni-ulm.de.
Cell Calcium ; 58(6): 628-37, 2015 Dec.
Article en En | MEDLINE | ID: mdl-26560688
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calcio / Vesículas Secretoras / Exocitosis / Ambroxol / Lisosomas Límite: Animals Idioma: En Revista: Cell Calcium Año: 2015 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calcio / Vesículas Secretoras / Exocitosis / Ambroxol / Lisosomas Límite: Animals Idioma: En Revista: Cell Calcium Año: 2015 Tipo del documento: Article Pais de publicación: Países Bajos