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Pharmacological chaperone for α-crystallin partially restores transparency in cataract models.
Makley, Leah N; McMenimen, Kathryn A; DeVree, Brian T; Goldman, Joshua W; McGlasson, Brittney N; Rajagopal, Ponni; Dunyak, Bryan M; McQuade, Thomas J; Thompson, Andrea D; Sunahara, Roger; Klevit, Rachel E; Andley, Usha P; Gestwicki, Jason E.
Afiliación
  • Makley LN; Departments of Pathology, Biological Chemistry, and Medicinal Chemistry and the Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
  • McMenimen KA; Departments of Pathology, Biological Chemistry, and Medicinal Chemistry and the Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
  • DeVree BT; Department of Pharmacology, University of Michigan, Ann Arbor, MI, USA.
  • Goldman JW; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
  • McGlasson BN; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
  • Rajagopal P; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Dunyak BM; Departments of Pathology, Biological Chemistry, and Medicinal Chemistry and the Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
  • McQuade TJ; Center for Chemical Genomics, University of Michigan, Ann Arbor, MI, USA.
  • Thompson AD; Departments of Pathology, Biological Chemistry, and Medicinal Chemistry and the Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
  • Sunahara R; Department of Pharmacology, University of Michigan, Ann Arbor, MI, USA.
  • Klevit RE; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Andley UP; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA. andley@vision.wustl.edu.
  • Gestwicki JE; Departments of Pathology, Biological Chemistry, and Medicinal Chemistry and the Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA. Center for Chemical Genomics, University of Michigan, Ann Arbor, MI, USA. andley@vision.wustl.edu.
Science ; 350(6261): 674-7, 2015 Nov 06.
Article en En | MEDLINE | ID: mdl-26542570
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Catarata / Cadena A de alfa-Cristalina / Cadena B de alfa-Cristalina / Hidroxicolesteroles Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Science Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Catarata / Cadena A de alfa-Cristalina / Cadena B de alfa-Cristalina / Hidroxicolesteroles Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Science Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos