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Genetic variation in V gene of class II Newcastle disease virus.
Hao, Huafang; Chen, Shengli; Liu, Peng; Ren, Shanhui; Gao, Xiaolong; Wang, Yanping; Wang, Xinglong; Zhang, Shuxia; Yang, Zengqi.
Afiliación
  • Hao H; College of Veterinary Medicine, Northwest A & F University, Yangling, 712100, Shaanxi, China.
  • Chen S; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 1, Lanzhou, 730046, Gansu, People's Republic of China.
  • Liu P; College of Veterinary Medicine, Northwest A & F University, Yangling, 712100, Shaanxi, China.
  • Ren S; College of Veterinary Medicine, Northwest A & F University, Yangling, 712100, Shaanxi, China.
  • Gao X; College of Veterinary Medicine, Northwest A & F University, Yangling, 712100, Shaanxi, China.
  • Wang Y; College of Veterinary Medicine, Northwest A & F University, Yangling, 712100, Shaanxi, China.
  • Wang X; College of Veterinary Medicine, Northwest A & F University, Yangling, 712100, Shaanxi, China.
  • Zhang S; College of Veterinary Medicine, Northwest A & F University, Yangling, 712100, Shaanxi, China.
  • Yang Z; College of Veterinary Medicine, Northwest A & F University, Yangling, 712100, Shaanxi, China. Electronic address: yzq8162@163.com.
Infect Genet Evol ; 37: 14-20, 2016 Jan.
Article en En | MEDLINE | ID: mdl-26527207
The genetic variation and molecular evolution of the V gene of the class II Newcastle disease virus (NDV) isolates with genotypes I-XVIII were determined using bioinformatics. Results indicated that low homology existed in different genotype viruses, whereas high homology often for the same genotypes, exception may be existed within genotypes I, V, VI, and XII. Sequence analysis showed that the genetic variation of V protein was consistent with virus genotype, and specific signatures on the V protein for nine genotypes were identified. Phylogenetic analysis demonstrated that the phylogenetic trees were highly consistent between the V and F genes, with slight discrepancies in the sub-genotypes. Evolutionary rate analyses based on V and F genes revealed the evolution rates varied in genotypes. These data indicate that the genetic variation of V protein is genotype-related and will help in elucidating the molecular evolution of NDV.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Virus de la Enfermedad de Newcastle / Polimorfismo de Nucleótido Simple Idioma: En Revista: Infect Genet Evol Asunto de la revista: BIOLOGIA / DOENCAS TRANSMISSIVEIS / GENETICA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Virus de la Enfermedad de Newcastle / Polimorfismo de Nucleótido Simple Idioma: En Revista: Infect Genet Evol Asunto de la revista: BIOLOGIA / DOENCAS TRANSMISSIVEIS / GENETICA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos