Co-activator binding protein PIMT mediates TNF-&#945; induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4.

Kain, Vasundhara; Kapadia, Bandish; Viswakarma, Navin; Seshadri, Sriram; Prajapati, Bhumika; Jena, Prasant K; Teja Meda, Chandana Lakshmi; Subramanian, Maitreyi; Kaimal Suraj, Sashidhara; Kumar, Sireesh T; Prakash Babu, Phanithi; Thimmapaya, Bayar; Reddy, Janardan K; Parsa, Kishore V L; Misra, Parimal

Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4.

Kain, Vasundhara; Kapadia, Bandish; Viswakarma, Navin; Seshadri, Sriram; Prajapati, Bhumika; Jena, Prasant K; Teja Meda, Chandana Lakshmi; Subramanian, Maitreyi; Kaimal Suraj, Sashidhara; Kumar, Sireesh T; Prakash Babu, Phanithi; Thimmapaya, Bayar; Reddy, Janardan K; Parsa, Kishore V L; Misra, Parimal.

Afiliación

Kain V; Department of Biology, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India.
Kapadia B; Department of Biology, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India.
Viswakarma N; Department of Biology, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India.
Seshadri S; Institute of Science, Nirma University, Sarkhej-Gandhinagar Highway, Ahmedabad, Gujarat, India.
Prajapati B; Institute of Science, Nirma University, Sarkhej-Gandhinagar Highway, Ahmedabad, Gujarat, India.
Jena PK; Institute of Science, Nirma University, Sarkhej-Gandhinagar Highway, Ahmedabad, Gujarat, India.
Teja Meda CL; Department of Biology, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India.
Subramanian M; Department of Biology, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India.
Kaimal Suraj S; Department of Biotechnology, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Kumar ST; Department of Biotechnology, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Prakash Babu P; Department of Biotechnology, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Thimmapaya B; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
Reddy JK; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
Parsa KV; Department of Biology, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India.
Misra P; Department of Biology, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India.

Sci Rep ; 5: 15197, 2015 Oct 15.

Article en En | MEDLINE | ID: mdl-26468734

Asunto(s)

Transportador de Glucosa de Tipo 4/metabolismo; Proteína D-Aspartato-L-Isoaspartato Metiltransferasa/metabolismo; Transcripción Genética/efectos de los fármacos; Factor de Necrosis Tumoral alfa/farmacología; Animales; Glucemia/análisis; Células Cultivadas; Regulación hacia Abajo/efectos de los fármacos; Transportador de Glucosa de Tipo 4/genética; Células HEK293; Histona Desacetilasas/genética; Histona Desacetilasas/metabolismo; Humanos; Resistencia a la Insulina; Factores de Transcripción MEF2/genética; Factores de Transcripción MEF2/metabolismo; Masculino; Proteína Quinasa 1 Activada por Mitógenos/metabolismo; Proteína Quinasa 3 Activada por Mitógenos/metabolismo; Mioblastos Esqueléticos/citología; Mioblastos Esqueléticos/metabolismo; Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma; Fosforilación/efectos de los fármacos; Proteína D-Aspartato-L-Isoaspartato Metiltransferasa/genética; Ratas; Ratas Wistar; Factores de Transcripción/genética; Factores de Transcripción/metabolismo; Factor de Necrosis Tumoral alfa/sangre

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transcripción Genética / Factor de Necrosis Tumoral alfa / Proteína D-Aspartato-L-Isoaspartato Metiltransferasa / Transportador de Glucosa de Tipo 4 Límite: Animals / Humans / Male Idioma: En Revista: Sci Rep Año: 2015 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido

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