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Pregnancy outcome after blastocyst stage transfer comparing to early cleavage stage embryo transfer.
Aziminekoo, Elham; Mohseni Salehi, Maryam Sadat; Kalantari, Vahid; Shahrokh Tehraninejad, Ensieh; Haghollahi, Fedyeh; Hossein Rashidi, Batool; Zandieh, Zahra.
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  • Aziminekoo E; a Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences , Tehran , Iran .
  • Mohseni Salehi MS; b Departments of Obstetrics and Gynecology , Vali-e-Asr Hospital, Tehran University of Medical Sciences , Tehran , Iran , and.
  • Kalantari V; c The American University of Integrative Sciences, St. Maarten School of Medicine , St. Maarten , USA.
  • Shahrokh Tehraninejad E; a Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences , Tehran , Iran .
  • Haghollahi F; a Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences , Tehran , Iran .
  • Hossein Rashidi B; a Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences , Tehran , Iran .
  • Zandieh Z; a Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences , Tehran , Iran .
Gynecol Endocrinol ; 31(11): 880-4, 2015.
Article en En | MEDLINE | ID: mdl-26437606
Blastocyst transfer has been introduced as an alternative for improving the chance for in vitro fertilizations (IVF) implantation. The present study was to evaluate pregnancy rates when embryo transfer was performed either on day 2-3 (cleavage stage) or on day 4-5 (blastocyst stage). This randomized clinical trial included 118 infertile women. All the study subjects underwent controlled ovarian stimulation using a long protocol and randomized into two groups. BS group (n = 57), the culture was extended to day 5 (blastocyst stage) and in the CS-group (n = 61), embryo culture was continued to day 3 (cleavage stage). Ongoing pregnancies, abortion, implantation rate were evaluated. No significant differences were seen in the pregnancy rate between the two groups (33.3% in the BS group versus 27.9% in the CS group; p = 0.519). Abortion, implantation rate in two groups are not significant. Despite the lack of statistical difference between the two study groups, our data suggest that blastocyst transfer may be associated with a higher pregnancy and an overall better implantation rates. However, further studies with larger sample size are mandatory to confirm these findings.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resultado del Embarazo / Fase de Segmentación del Huevo / Índice de Embarazo / Técnicas de Cultivo de Embriones / Transferencia de Embrión / Infertilidad Femenina Tipo de estudio: Clinical_trials / Guideline Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Gynecol Endocrinol Asunto de la revista: ENDOCRINOLOGIA / GINECOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resultado del Embarazo / Fase de Segmentación del Huevo / Índice de Embarazo / Técnicas de Cultivo de Embriones / Transferencia de Embrión / Infertilidad Femenina Tipo de estudio: Clinical_trials / Guideline Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Gynecol Endocrinol Asunto de la revista: ENDOCRINOLOGIA / GINECOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido