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Photoacoustic imaging of cerebral hypoperfusion during acupuncture.
Chen, B Z; Yang, J G; Wu, D; Zeng, D W; Yi, Y; Yang, N; Jiang, H B.
Afiliación
  • Chen BZ; School of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, 610054, China.
  • Yang JG; School of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, 610054, China.
  • Wu D; School of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, 610054, China.
  • Zeng DW; Institute of Laboratory Animals of Sichuan Academy of Medical Sciences and Sichuan Province People's Hospital, Chengdu, 610054, China.
  • Yi Y; Institute of Laboratory Animals of Sichuan Academy of Medical Sciences and Sichuan Province People's Hospital, Chengdu, 610054, China.
  • Yang N; Institute of Laboratory Animals of Sichuan Academy of Medical Sciences and Sichuan Province People's Hospital, Chengdu, 610054, China.
  • Jiang HB; School of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, 610054, China ; Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA.
Biomed Opt Express ; 6(9): 3225-34, 2015 Sep 01.
Article en En | MEDLINE | ID: mdl-26417495
Using acupuncture to treat cerebral hypoperfusion is a hot topic. However, there is a lack of effective tools to clarify the therapeutic effect of acupuncture on cerebral hypoperfusion. Here, we show in a mouse model of cerebral hypoperfusion that photoacoustic tomography (PAT) can noninvasively image cerebral vasculature and track total hemoglobin (HbT) concentration changes in cerebral hypoperfusion with acupuncture stimulation on the YangLingQuan (GB34) point. We measured the changes of HbT concentration and found that the HbT concentration in hypoperfusion regions was clearly lower than that in the control regions when the acupuncture was absent; however, it was significantly increased when the acupuncture was implemented on the GB34 point. We also observed the increase of vessel size and the generation of new vessels in cerebral hypoperfusion during acupuncture. Laser speckle imaging (LSI) was employed to validate some of the PAT findings.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Biomed Opt Express Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Biomed Opt Express Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos