[THE ROLE OF ENDOTHELIAL SIGNAL MOLECULES IN PATHOGENESIS OF AGE-ASSOCIATED DISEASES].
Adv Gerontol
; 28(1): 29-36, 2015.
Article
en Ru
| MEDLINE
| ID: mdl-26390607
The article gives a summary of endothelial signal molecules that take part in homeostasis regulation and age-associated pathology development. Regulation of the endothelium function is realized by the system of signal molecules (NO, NOS, prostacyclin, thrombomodulin, tromboxan, antithrombin, endothelins, fibronectin, Willebrand's factor et al.). The change of their synthesis is the reason for the development of hypertonic disease, atherosclerosis, ischemic heart disease, myocardial infarction and other age-related pathology. The investigation of molecular mechanisms of endothelium functional activity is very important for creating new methods of diagnostics and treatment of cardio-vascular system age-associated pathology.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Endotelio Vascular
/
Aterosclerosis
/
Lípidos
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Aged
/
Humans
Idioma:
Ru
Revista:
Adv Gerontol
Asunto de la revista:
GERIATRIA
Año:
2015
Tipo del documento:
Article
Pais de publicación:
Rusia