Your browser doesn't support javascript.
loading
Institutionalization and indiscriminate social behavior: Differential-susceptibility versus diathesis-stress models for the 5-HTTLPR and BDNF genotypes.
Mesquita, A R; Belsky, J; Li, Z; Baptista, J; Carvalho-Correia, E; Maciel, P; Soares, I.
Afiliación
  • Mesquita AR; Neuropsychophysiology Lab, CIPsi, School of Psychology, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal. Electronic address: ana.mesquita@psi.uminho.uminho.pt.
  • Belsky J; Department of Human Ecology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: jbelsky@ucdavis.edu.
  • Li Z; Department of Human Ecology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: zhdli@ucdavis.edu.
  • Baptista J; Psychotherapy and Psychopathology Research Unit, CIPsi, School of Psychology, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal. Electronic address: joana.baptista.mail@gmail.com.
  • Carvalho-Correia E; Psychotherapy and Psychopathology Research Unit, CIPsi, School of Psychology, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal. Electronic address: eduardaicorreia@ecsaude.uminho.pt.
  • Maciel P; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal; ICVS/3Bs, PT Government Associate Laboratory, Braga, Guimarães, Portugal. Electronic address: pmaciel@ecsaude.uminho.pt.
  • Soares I; Psychotherapy and Psychopathology Research Unit, CIPsi, School of Psychology, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal. Electronic address: isoares@psi.uminho.pt.
Physiol Behav ; 152(Pt A): 85-91, 2015 Dec 01.
Article en En | MEDLINE | ID: mdl-26386404
Institutionalization adversely impacts children's emotional functioning, proving related to attachment disorders, perhaps most notably that involving indiscriminate behavior, the subject of this report. In seeking to extend work in this area, this research on gene X environment (GXE) interplay investigated whether the serotonin transporter (5-HTTLPR) and val66met Brain-Derived Neurotrophic Factor (BDNF) polymorphisms moderated the effect of institutional care on indiscriminate behavior in preschoolers. Eighty-five institutionalized and 135 home-reared Portuguese children were assessed using Disturbances of Attachment Interview (DAI). GXE results indicated that s/s homozygotes of the 5-HTTLPR gene displayed significantly higher levels of indiscriminate behavior than all other children if institutionalized, something not true of such children when family reared. These findings proved consistent with the diathesis-stress rather than differential-susceptibility model of person×environment interaction. BDNF proved unrelated to indiscriminate behavior. Results are discussed in relation to previous work on this subject of indiscriminate behavior, institutionalization and GXE interaction.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo Genético / Conducta Social / Niño Institucionalizado / Factor Neurotrófico Derivado del Encéfalo / Proteínas de Transporte de Serotonina en la Membrana Plasmática / Apego a Objetos Tipo de estudio: Prognostic_studies / Qualitative_research Aspecto: Determinantes_sociais_saude Límite: Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Europa Idioma: En Revista: Physiol Behav Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo Genético / Conducta Social / Niño Institucionalizado / Factor Neurotrófico Derivado del Encéfalo / Proteínas de Transporte de Serotonina en la Membrana Plasmática / Apego a Objetos Tipo de estudio: Prognostic_studies / Qualitative_research Aspecto: Determinantes_sociais_saude Límite: Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Europa Idioma: En Revista: Physiol Behav Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos