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Targeted delivery of the hydroxylase inhibitor DMOG provides enhanced efficacy with reduced systemic exposure in a murine model of colitis.
Tambuwala, Murtaza M; Manresa, Mario C; Cummins, Eoin P; Aversa, Vincenzo; Coulter, Ivan S; Taylor, Cormac T.
Afiliación
  • Tambuwala MM; School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine, County Londonderry BT52 1SA, Northern Ireland.
  • Manresa MC; School of Medicine and Medical Science, The Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.
  • Cummins EP; School of Medicine and Medical Science, The Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.
  • Aversa V; Sigmoid Pharma Ltd., Dublin, Ireland.
  • Coulter IS; Sigmoid Pharma Ltd., Dublin, Ireland.
  • Taylor CT; School of Medicine and Medical Science, The Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address: cormac.taylor@ucd.ie.
J Control Release ; 217: 221-7, 2015 Nov 10.
Article en En | MEDLINE | ID: mdl-26385165
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colitis / Aminoácidos Dicarboxílicos / Oxigenasas de Función Mixta Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: J Control Release Asunto de la revista: FARMACOLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colitis / Aminoácidos Dicarboxílicos / Oxigenasas de Función Mixta Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: J Control Release Asunto de la revista: FARMACOLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: Países Bajos