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Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide.
Alam, Shirjel R; Stirrat, Colin; Richards, Jennifer; Mirsadraee, Saeed; Semple, Scott I K; Tse, George; Henriksen, Peter; Newby, David E.
Afiliación
  • Alam SR; Centre for Cardiovascular Science, The University of Edinburgh, The Chancellor's Building, Little France Crescent, Edinburgh, EH16 5SA, UK. s.r.alam@sms.ed.ac.uk.
  • Stirrat C; Department of Cardiology, Royal Infirmary of Edinburgh, Edinburgh, EH16 5SA, UK. s.r.alam@sms.ed.ac.uk.
  • Richards J; Centre for Cardiovascular Science, The University of Edinburgh, The Chancellor's Building, Little France Crescent, Edinburgh, EH16 5SA, UK. cstirrat@exseed.ed.ac.uk.
  • Mirsadraee S; Department of Cardiology, Royal Infirmary of Edinburgh, Edinburgh, EH16 5SA, UK. cstirrat@exseed.ed.ac.uk.
  • Semple SI; Centre for Cardiovascular Science, The University of Edinburgh, The Chancellor's Building, Little France Crescent, Edinburgh, EH16 5SA, UK. jenny.Robson@ed.ac.uk.
  • Tse G; Clinical Research Imaging Centre, University of Edinburgh, Edinburgh, EH16 5SA, UK. Saeed.Mirsadraee@ed.ac.uk.
  • Henriksen P; Department of Radiology, Royal Infirmary of Edinburgh, Edinburgh, EH16 5SA, UK. Saeed.Mirsadraee@ed.ac.uk.
  • Newby DE; Clinical Research Imaging Centre, University of Edinburgh, Edinburgh, EH16 5SA, UK. scott.semple@ed.ac.u.
J Cardiovasc Magn Reson ; 17: 83, 2015 Sep 18.
Article en En | MEDLINE | ID: mdl-26381872
Cardiovascular Magnetic Resonance (CMR) has become a primary tool for non-invasive assessment of cardiovascular anatomy, pathology and function. Existing contrast agents have been utilised for the identification of infarction, fibrosis, perfusion deficits and for angiography. Novel ultrasmall superparamagnetic particles of iron oxide (USPIO) contrast agents that are taken up by inflammatory cells can detect cellular inflammation non-invasively using CMR, potentially aiding the diagnosis of inflammatory medical conditions, guiding their treatment and giving insight into their pathophysiology. In this review we describe the utilization of USPIO as a novel contrast agent in vascular disease.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arterias / Imagen por Resonancia Magnética / Dextranos / Medios de Contraste / Aterosclerosis / Placa Aterosclerótica / Nanopartículas de Magnetita / Inflamación / Macrófagos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Cardiovasc Magn Reson Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / DIAGNOSTICO POR IMAGEM Año: 2015 Tipo del documento: Article Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arterias / Imagen por Resonancia Magnética / Dextranos / Medios de Contraste / Aterosclerosis / Placa Aterosclerótica / Nanopartículas de Magnetita / Inflamación / Macrófagos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Cardiovasc Magn Reson Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / DIAGNOSTICO POR IMAGEM Año: 2015 Tipo del documento: Article Pais de publicación: Reino Unido