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Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration.
Xiang, Wei; Cheong, Jit Kong; Ang, Shi Hui; Teo, Bryan; Xu, Peng; Asari, Kartini; Sun, Wen Tian; Than, Hein; Bunte, Ralph M; Virshup, David M; Chuah, Charles.
Afiliación
  • Xiang W; Department of Haematology, Singapore General Hospital, Singapore.
  • Cheong JK; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore.
  • Ang SH; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore.
  • Teo B; Department of Haematology, Singapore General Hospital, Singapore.
  • Xu P; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore.
  • Asari K; Department of Haematology, Singapore General Hospital, Singapore.
  • Sun WT; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore.
  • Than H; Department of Haematology, Singapore General Hospital, Singapore.
  • Bunte RM; Office of Research, Duke-NUS Graduate Medical School, Singapore.
  • Virshup DM; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore.
  • Chuah C; Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Oncotarget ; 6(32): 33769-80, 2015 Oct 20.
Article en En | MEDLINE | ID: mdl-26378050
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Pirvinio / Leucemia Mielógena Crónica BCR-ABL Positiva / Mitocondrias Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2015 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Pirvinio / Leucemia Mielógena Crónica BCR-ABL Positiva / Mitocondrias Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2015 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Estados Unidos