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Nanoparticle-based imaging of inflammatory bowel disease.
Wu, Yingwei; Briley, Karen; Tao, Xiaofeng.
Afiliación
  • Wu Y; Department of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
  • Briley K; Department of Radiology, Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, China.
  • Tao X; Department of Radiology, Wright Center of Innovation and Biomedical Imaging, The Ohio State University, Columbus, OH, USA.
Wiley Interdiscip Rev Nanomed Nanobiotechnol ; 8(2): 300-15, 2016.
Article en En | MEDLINE | ID: mdl-26371464
Although inflammatory bowel disease (IBD) has been extensively studied, the pathogenesis is still not completely understood. As a result, the treatment options remain unsatisfactory and nonspecific. With the rapid advancement of diagnostic imaging techniques, imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) are playing a more important role in IBD diagnosis and evaluation. Recent developments in nanotechnology utilize an interdisciplinary approach to specifically target molecular or cellular IBD pathological process thereby generating nanoparticles (NPs) with high specificity and diagnostic and/or therapeutic efficacy. Nano-based imaging, which incorporates nanotechnology and imaging modalities, may allow for the early detection of IBD, the monitoring of disease activity, and may be used to monitor the therapeutic response at cellular and/or molecular level. In this review, we highlight issues related to nano-based imaging and its application in IBD field.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diagnóstico por Imagen / Enfermedades Inflamatorias del Intestino / Nanopartículas Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Wiley Interdiscip Rev Nanomed Nanobiotechnol Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diagnóstico por Imagen / Enfermedades Inflamatorias del Intestino / Nanopartículas Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Wiley Interdiscip Rev Nanomed Nanobiotechnol Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos