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Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation.
Cattin, Marie-Elodie; Wang, Jessica; Weldrick, Jonathan J; Roeske, Cassandra L; Mak, Esther; Thorn, Stephanie L; DaSilva, Jean N; Wang, Yibin; Lusis, Aldon J; Burgon, Patrick G.
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  • Cattin ME; From the University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7, Canada.
  • Wang J; the Departments of Medicine.
  • Weldrick JJ; From the University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7, Canada, the Departments of Cellular and Molecular Medicine, and Medicine (Cardiology), Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
  • Roeske CL; From the University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7, Canada.
  • Mak E; From the University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7, Canada.
  • Thorn SL; From the University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7, Canada, the Departments of Cellular and Molecular Medicine, and Medicine (Cardiology), Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
  • DaSilva JN; From the University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7, Canada, the Departments of Cellular and Molecular Medicine, and Medicine (Cardiology), Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
  • Wang Y; Anesthesiology, Physiology & Medicine, and.
  • Lusis AJ; Microbiology, Immunology and Molecular Genetics, Human Genetics & Medicine, Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, and.
  • Burgon PG; From the University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7, Canada, the Departments of Cellular and Molecular Medicine, and Medicine (Cardiology), Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada pburgon@ottawaheart.ca.
J Biol Chem ; 290(44): 26699-714, 2015 Oct 30.
Article en En | MEDLINE | ID: mdl-26359501
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Proteínas Portadoras / Cardiomegalia / Proteínas Proto-Oncogénicas c-akt / Serina-Treonina Quinasas TOR / Miocardio Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Proteínas Portadoras / Cardiomegalia / Proteínas Proto-Oncogénicas c-akt / Serina-Treonina Quinasas TOR / Miocardio Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos