Immobilization of Antibody on a Cyclic Olefin Copolymer Surface with Functionalizable, Non-Biofouling Poly[Oligo(Ethylene Glycol) Methacrylate].
J Nanosci Nanotechnol
; 15(2): 1767-70, 2015 Feb.
Article
en En
| MEDLINE
| ID: mdl-26353730
We report a perfluoroaryl azide-based photoreaction for synthesizing functionalizable and nonbiofouling poly[oligo(ethylene glycol) methacrylate] (pOEGMA) films on a chemically inert COC substrate, and an estimation of a surface coverage of the antibody immobilized onto the surface with the immuno-gold nanoparticles. The processes were confirmed by water contact angle measurement, FT-IR spectroscopy, and FE-SEM. The strategy demonstrated in this work could be applied to functionalizations of other polymeric materials and determination of the binding capacity of analytes in biosensors and microfluidic devices.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polietilenglicoles
/
Alquenos
/
Nanopartículas del Metal
/
Nanoconjugados
/
Oro
/
Metacrilatos
/
Anticuerpos
Límite:
Animals
Idioma:
En
Revista:
J Nanosci Nanotechnol
Año:
2015
Tipo del documento:
Article
Pais de publicación:
Estados Unidos