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Immunoregulation on Mice of Low Immunity and Effects on Five Kinds of Human Cancer Cells of Panax japonicus Polysaccharide.
Jie, Zhang; Chun-Yan, Li; Jing-Ping, Li; Ren, Guo; Hui, Wang; Juan, Pan; Sheng-Lan, Liu.
Afiliación
  • Jie Z; Third Xiangya Hospital, Central South University, Changsha 410013, China.
  • Chun-Yan L; Third Xiangya Hospital, Central South University, Changsha 410013, China ; Changsha University, Changsha 410022, China.
  • Jing-Ping L; School of Pharmaceutical Science, Central South University, Changsha 410013, China.
  • Ren G; Third Xiangya Hospital, Central South University, Changsha 410013, China.
  • Hui W; The Central Hospital of Taian, Taian 271000, China.
  • Juan P; Maternal and Child Health Hospital, Liuyang 410300, China.
  • Sheng-Lan L; Third Xiangya Hospital, Central South University, Changsha 410013, China.
Evid Based Complement Alternat Med ; 2015: 839697, 2015.
Article en En | MEDLINE | ID: mdl-26345429
The goal of this study is to investigate the immunoregulative effects of Panax japonicus polysaccharide (PJPS) on mice of low immunity. An orthogonal experiment was designed to determine the best extraction process for PJPS. By the tests of macrophages swallow chicken red blood cells, Delayed-type hypersensitivity (DTH), and serum hemolysin value, we studied the immune adjustment ability of PJPS. MTT was employed to detect the effects of different concentrations of PJPS, respectively, in 24 h, 48 h, and 72 h on five kinds of human cancer cells. The results show that the best extraction process for PJPS was as follows: ratio of solvent consumption to raw material 40, extraction temperature 100°C, re-extracted two times, each extraction time 4 hours. PJPS can significantly improve the immune function of mice processed by cyclophosphamide and PJPS did not work on the above five cancer cells.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Evid Based Complement Alternat Med Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Evid Based Complement Alternat Med Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos