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Prevention of Esophageal Stricture After Endoscopic Submucosal Dissection: A Systematic Review.
Yu, Jiang-Ping; Liu, Yong-Jun; Tao, Ya-Li; Ruan, Rong-Wei; Cui, Zhao; Zhu, Shu-Wen; Shi, Wang.
Afiliación
  • Yu JP; Department of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
  • Liu YJ; Department of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
  • Tao YL; Department of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
  • Ruan RW; Department of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
  • Cui Z; Department of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
  • Zhu SW; Department of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
  • Shi W; Department of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China. wangsh357@sina.com.
World J Surg ; 39(12): 2955-64, 2015 Dec.
Article en En | MEDLINE | ID: mdl-26335901
BACKGROUND: Endoscopic submucosal dissection (ESD) is rapidly becoming a favored method for removing early esophageal cancer, but the residual defects can be complicated with strictures that require repeated endoscopic balloon dilatation. Measures for preventing the post-ESD strictures have been sought. We conducted a systematic review of recent studies to evaluate these methods. METHODS: We searched MEDLINE, Cochrane Central Register of Controlled Trials, Embase, and Google Scholar until November 30, 2014. Included studies were prospective and retrospective one- and two-arm studies. All studies had to include at least on preventive method for post-ESD stricture. Thirteen studies were included in the review. RESULTS: Among the studies that used corticosteroids to prevent post-ESD stricture, we found that (1) injection of triamcinolone acetonide into the esophageal lesion resulted in a substantial reduction in the rate of stricture, and (2) the use of oral prednisolone was associated with a significantly reduced rate of dilatation sessions and stricture. Studies of other preventative measures included more recently developed scaffold-based and cell-based tissue-engineering approaches which seem very promising but require additional rigorously controlled studies to test their effectiveness. CONCLUSIONS: Until a safer and more effective method is developed, our review supports the use of corticosteroids, either through injection or oral route, together with endoscopic dilatation in prevention of post-ESD strictures.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Disección / Estenosis Esofágica / Membrana Mucosa Tipo de estudio: Etiology_studies / Systematic_reviews Límite: Humans Idioma: En Revista: World J Surg Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Disección / Estenosis Esofágica / Membrana Mucosa Tipo de estudio: Etiology_studies / Systematic_reviews Límite: Humans Idioma: En Revista: World J Surg Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos