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Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.
Xia, Hong-Guang; Najafov, Ayaz; Geng, Jiefei; Galan-Acosta, Lorena; Han, Xuemei; Guo, Yuan; Shan, Bing; Zhang, Yaoyang; Norberg, Erik; Zhang, Tao; Pan, Lifeng; Liu, Junli; Coloff, Jonathan L; Ofengeim, Dimitry; Zhu, Hong; Wu, Kejia; Cai, Yu; Yates, John R; Zhu, Zhengjiang; Yuan, Junying; Vakifahmetoglu-Norberg, Helin.
Afiliación
  • Xia HG; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Najafov A; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Geng J; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Galan-Acosta L; Division of Toxicology, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
  • Han X; The Scripps Research Institute, Department of Chemical Physiology SR11, San Diego, CA 92121.
  • Guo Y; Interdisciplinary Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Shan B; Interdisciplinary Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Zhang Y; Interdisciplinary Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Norberg E; Division of Toxicology, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
  • Zhang T; Interdisciplinary Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Pan L; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Liu J; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Coloff JL; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Ofengeim D; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Zhu H; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Wu K; Interdisciplinary Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Cai Y; Interdisciplinary Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Yates JR; The Scripps Research Institute, Department of Chemical Physiology SR11, San Diego, CA 92121.
  • Zhu Z; Interdisciplinary Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Yuan J; Department of Cell Biology, Harvard Medical School, Boston, MA 02115 Interdisciplinary Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China jyuan@hms.harvard.edu.
  • Vakifahmetoglu-Norberg H; Department of Cell Biology, Harvard Medical School, Boston, MA 02115 Division of Toxicology, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
J Cell Biol ; 210(5): 705-16, 2015 Aug 31.
Article en En | MEDLINE | ID: mdl-26323688
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Leucemia Mieloide / Chaperonas Moleculares / Tirosina Quinasa 3 Similar a fms / Proteolisis / Hexoquinasa Límite: Humans Idioma: En Revista: J Cell Biol Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Leucemia Mieloide / Chaperonas Moleculares / Tirosina Quinasa 3 Similar a fms / Proteolisis / Hexoquinasa Límite: Humans Idioma: En Revista: J Cell Biol Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos