Deciphering the biochemistry and identifying biomarkers to multiple sclerosis.

Martins-de-Souza, Daniel; Farias, Alessandro S

Martins-de-Souza, Daniel; Farias, Alessandro S.

Afiliación

Martins-de-Souza D; UNICAMP's Neurobiology Center, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Farias AS; Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.

Proteomics ; 15(19): 3281-2, 2015 Oct.

Article en En | MEDLINE | ID: mdl-26314682

RESUMEN

Multiple sclerosis is an idiopathic demyelinating disease of the CNS. Despite being extensively studied during the last decades, many molecular aspects of the disease are still to be elucidated. Moreover, biomarkers for treatment and early diagnosis are major issues to be tackled. In this edition of Kroksveen et al. (Proteomics 2015, 15, 3361-3369) present biomarker candidates for the early detection of multiple sclerosis. Despite the need for validation in larger sets of samples, this dataset contributes to resolve open questions associated to multiple sclerosis.

Asunto(s)

Cromogranina B/líquido cefalorraquídeo; Esclerosis Múltiple/líquido cefalorraquídeo; Femenino; Humanos; Masculino

Palabras clave

Biomarkers; Cerebrospinal fluid; Multiple sclerosis; Quantitative MS; Secretogranin-1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromogranina B / Esclerosis Múltiple Tipo de estudio: Screening_studies Límite: Female / Humans / Male Idioma: En Revista: Proteomics Asunto de la revista: BIOQUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Alemania

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