One new cycloartane triterpene glycoside from Beesia calthaefolia.
Nat Prod Res
; 30(3): 316-21, 2016.
Article
en En
| MEDLINE
| ID: mdl-26305784
One new cycloartane triterpene glycoside (1) was isolated from the whole plant of Beesia calthaefolia. Its structure was elucidated on the basis of extensive spectroscopic data analysis. Its inhibitory effect was measured by the classical pathway of the complement system, and compared with those of known related cycloartane glycosides 2 and 3, previously isolated by us from the same plant. Compounds 1 and 2 exhibited inhibitory activity of complement system with IC50 of 395.3 and 214 µM, respectively. The results suggested that OH at C-12, C-18 and C-15 along with the polarity could affect the inhibitory activity.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Triterpenos
/
Ranunculaceae
/
Glicósidos
Límite:
Animals
Idioma:
En
Revista:
Nat Prod Res
Año:
2016
Tipo del documento:
Article
Pais de publicación:
Reino Unido