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Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes.
Tiffen, Jessamy C; Gunatilake, Dilini; Gallagher, Stuart J; Gowrishankar, Kavitha; Heinemann, Anja; Cullinane, Carleen; Dutton-Regester, Ken; Pupo, Gulietta M; Strbenac, Dario; Yang, Jean Y; Madore, Jason; Mann, Graham J; Hayward, Nicholas K; McArthur, Grant A; Filipp, Fabian V; Hersey, Peter.
Afiliación
  • Tiffen JC; Melanoma Immunology and Oncology Group, Centenary Institute, University of Sydney, NSW, Australia.
  • Gunatilake D; Melanoma Research Group, Kolling Institute of Medical Research, University of Sydney, NSW, Australia.
  • Gallagher SJ; Melanoma Institute Australia, Crows Nest, Sydney, NSW, Australia.
  • Gowrishankar K; Melanoma Immunology and Oncology Group, Centenary Institute, University of Sydney, NSW, Australia.
  • Heinemann A; Melanoma Research Group, Kolling Institute of Medical Research, University of Sydney, NSW, Australia.
  • Cullinane C; Melanoma Institute Australia, Crows Nest, Sydney, NSW, Australia.
  • Dutton-Regester K; Melanoma Immunology and Oncology Group, Centenary Institute, University of Sydney, NSW, Australia.
  • Pupo GM; Melanoma Research Group, Kolling Institute of Medical Research, University of Sydney, NSW, Australia.
  • Strbenac D; Melanoma Institute Australia, Crows Nest, Sydney, NSW, Australia.
  • Yang JY; Melanoma Immunology and Oncology Group, Centenary Institute, University of Sydney, NSW, Australia.
  • Madore J; Melanoma Research Group, Kolling Institute of Medical Research, University of Sydney, NSW, Australia.
  • Mann GJ; Melanoma Institute Australia, Crows Nest, Sydney, NSW, Australia.
  • Hayward NK; Melanoma Immunology and Oncology Group, Centenary Institute, University of Sydney, NSW, Australia.
  • McArthur GA; Melanoma Research Group, Kolling Institute of Medical Research, University of Sydney, NSW, Australia.
  • Filipp FV; Melanoma Institute Australia, Crows Nest, Sydney, NSW, Australia.
  • Hersey P; Translational Research Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Oncotarget ; 6(29): 27023-36, 2015 Sep 29.
Article en En | MEDLINE | ID: mdl-26304929
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Genes Supresores de Tumor / Complejo Represivo Polycomb 2 / Melanoma Límite: Humans Idioma: En Revista: Oncotarget Año: 2015 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Genes Supresores de Tumor / Complejo Represivo Polycomb 2 / Melanoma Límite: Humans Idioma: En Revista: Oncotarget Año: 2015 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos