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Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo.
Teramachi, J; Silbermann, R; Yang, P; Zhao, W; Mohammad, K S; Guo, J; Anderson, J L; Zhou, D; Feng, R; Myint, K-Z; Maertz, N; Beumer, J H; Eiseman, J L; Windle, J J; Xie, X-Q; Roodman, G D; Kurihara, N.
Afiliación
  • Teramachi J; Department of Medicine, Hematology Oncology, Indiana University, Indianapolis, IN, USA.
  • Silbermann R; Department of Medicine, Hematology Oncology, Indiana University, Indianapolis, IN, USA.
  • Yang P; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
  • Zhao W; Computational Chemical Genomics Screening Center, University of Pittsburgh, Pittsburgh, PA, USA.
  • Mohammad KS; Department of Medicine, Hematology Oncology, Indiana University, Indianapolis, IN, USA.
  • Guo J; Division of Endocrinology, Department of Medicine, Indiana University, Indianapolis, IN, USA.
  • Anderson JL; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.
  • Zhou D; Department of Medicine, Hematology Oncology, Indiana University, Indianapolis, IN, USA.
  • Feng R; Department of Medicine, Hematology Oncology, Indiana University, Indianapolis, IN, USA.
  • Myint KZ; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
  • Maertz N; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
  • Beumer JH; Department of Radiology, Indiana University, Indianapolis, IN, USA.
  • Eiseman JL; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
  • Windle JJ; Molecular Therapeutics/Drug Discovery Program, University of Pittsburgh, Pittsburgh, PA, USA.
  • Xie XQ; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.
  • Roodman GD; Molecular Therapeutics/Drug Discovery Program, University of Pittsburgh, Pittsburgh, PA, USA.
  • Kurihara N; Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Leukemia ; 30(2): 390-8, 2016 Feb.
Article en En | MEDLINE | ID: mdl-26286116
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoclastos / Osteogénesis / Proteínas Adaptadoras Transductoras de Señales / Mieloma Múltiple Tipo de estudio: Prognostic_studies Límite: Aged / Animals / Female / Humans / Male Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoclastos / Osteogénesis / Proteínas Adaptadoras Transductoras de Señales / Mieloma Múltiple Tipo de estudio: Prognostic_studies Límite: Aged / Animals / Female / Humans / Male Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido