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Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics.
Shalev, Moran; Rozenberg, Haim; Smolkin, Boris; Nasereddin, Abedelmajeed; Kopelyanskiy, Dmitry; Belakhov, Valery; Schrepfer, Thomas; Schacht, Jochen; Jaffe, Charles L; Adir, Noam; Baasov, Timor.
Afiliación
  • Shalev M; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, Israel Department of Structural Biology, Faculty of Chemistry, Weizmann Institute of Science, Rehovot, Israel.
  • Rozenberg H; Department of Structural Biology, Faculty of Chemistry, Weizmann Institute of Science, Rehovot, Israel.
  • Smolkin B; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, Israel.
  • Nasereddin A; Department of Microbiology and Molecular Genetics, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
  • Kopelyanskiy D; Department of Microbiology and Molecular Genetics, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
  • Belakhov V; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, Israel.
  • Schrepfer T; Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Schacht J; Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Jaffe CL; Department of Microbiology and Molecular Genetics, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
  • Adir N; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, Israel.
  • Baasov T; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, Israel chtimor@techunix.technion.ac.il.
Nucleic Acids Res ; 43(17): 8601-13, 2015 Sep 30.
Article en En | MEDLINE | ID: mdl-26264664
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ribosomas / Inhibidores de la Síntesis de la Proteína / Paromomicina / Leishmania / Antiprotozoarios Límite: Animals / Humans / Male Idioma: En Revista: Nucleic Acids Res Año: 2015 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ribosomas / Inhibidores de la Síntesis de la Proteína / Paromomicina / Leishmania / Antiprotozoarios Límite: Animals / Humans / Male Idioma: En Revista: Nucleic Acids Res Año: 2015 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Reino Unido