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Inverse relationship between body mass index and mortality in older nursing home residents: a meta-analysis of 19,538 elderly subjects.
Veronese, N; Cereda, E; Solmi, M; Fowler, S A; Manzato, E; Maggi, S; Manu, P; Abe, E; Hayashi, K; Allard, J P; Arendt, B M; Beck, A; Chan, M; Audrey, Y J P; Lin, W-Y; Hsu, H-S; Lin, C-C; Diekmann, R; Kimyagarov, S; Miller, M; Cameron, I D; Pitkälä, K H; Lee, J; Woo, J; Nakamura, K; Smiley, D; Umpierrez, G; Rondanelli, M; Sund-Levander, M; Valentini, L; Schindler, K; Törmä, J; Volpato, S; Zuliani, G; Wong, M; Lok, K; Kane, J M; Sergi, G; Correll, C U.
Afiliación
  • Veronese N; Department of Medicine - DIMED, Geriatrics Section, University of Padova, Padova, Italy.
  • Cereda E; Nutrition and Dietetics Service, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Solmi M; Department of Neurosciences, University of Padova, Padova, Italy.
  • Fowler SA; Becker Medical Library, Washington University, St. Louis, MO, USA.
  • Manzato E; Department of Medicine - DIMED, Geriatrics Section, University of Padova, Padova, Italy.
  • Maggi S; National Research Council, Institute of Neuroscience, Padova, Italy.
  • Manu P; National Research Council, Institute of Neuroscience, Padova, Italy.
  • Abe E; The Zucker Hillside Hospital, Psychiatry Research, North Shore - Long Island Jewish Health System, Glen Oaks, New York, USA.
  • Hayashi K; Hofstra North Shore LIJ School of Medicine, Hempstead, New York, USA.
  • Allard JP; The Feinstein Institute for Medical Research, Manhasset, New York, USA.
  • Arendt BM; Albert Einstein College of Medicine, Bronx, New York, USA.
  • Beck A; Gunma University Graduate School of Health Sciences, Maebashi, Gunma, Japan.
  • Chan M; Gunma University Graduate School of Health Sciences, Maebashi, Gunma, Japan.
  • Audrey YJ; Toronto General Hospital, University Health Network, Toronto, Canada.
  • Lin WY; Department of Medicine, University of Toronto, Toronto, Canada.
  • Hsu HS; Toronto General Hospital, University Health Network, Toronto, Canada.
  • Lin CC; Research Unit for Nutrition (EFFECT), Herlev University Hospital, Herlev, Denmark.
  • Diekmann R; Department of Geriatric Medicine, Tan Tock Seng Hospital, Jalan Tan Tock Seng, Singapore.
  • Kimyagarov S; Department of Geriatric Medicine, Tan Tock Seng Hospital, Jalan Tan Tock Seng, Singapore.
  • Miller M; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Cameron ID; School of Medicine, China Medical University, Taichung, Taiwan.
  • Pitkälä KH; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Lee J; School of Medicine, China Medical University, Taichung, Taiwan.
  • Woo J; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Nakamura K; School of Medicine, China Medical University, Taichung, Taiwan.
  • Smiley D; Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nürnberg, Germany.
  • Umpierrez G; The Gilad Geriatric Center, Ramat-Gan, Israel.
  • Rondanelli M; Nutrition and Dietetics, Flinders University, Adelaide, Australia.
  • Sund-Levander M; Walsh Centre for Rehabilitation Research, University of Sydney, Sydney, Australia.
  • Valentini L; Unit of Primary Health Care, Department of General Practice, Helsinki University Central Hospital, Helsinki, Finland.
  • Schindler K; The S. H. Ho Center for Gerontology and Geriatrics, The Chinese University of Hong Kong, Hong Kong, China.
  • Törmä J; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
  • Volpato S; The S. H. Ho Center for Gerontology and Geriatrics, The Chinese University of Hong Kong, Hong Kong, China.
  • Zuliani G; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
  • Wong M; Division of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
  • Lok K; Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
  • Kane JM; Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
  • Sergi G; Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, University of Pavia, Pavia, Italy.
  • Correll CU; Faculty of Health Sciences, University of Linköping, Linköping, Sweden.
Obes Rev ; 16(11): 1001-15, 2015 Nov.
Article en En | MEDLINE | ID: mdl-26252230
Body mass index (BMI) and mortality in old adults from the general population have been related in a U-shaped or J-shaped curve. However, limited information is available for elderly nursing home populations, particularly about specific cause of death. A systematic PubMed/EMBASE/CINAHL/SCOPUS search until 31 May 2014 without language restrictions was conducted. As no published study reported mortality in standard BMI groups (<18.5, 18.5-24.9, 25-29.9, ≥30 kg/m(2)), the most adjusted hazard ratios (HRs) according to a pre-defined list of covariates were obtained from authors and pooled by random-effect model across each BMI category. Out of 342 hits, 20 studies including 19,538 older nursing home residents with 5,223 deaths during a median of 2 years of follow-up were meta-analysed. Compared with normal weight, all-cause mortality HRs were 1.41 (95% CI = 1.26-1.58) for underweight, 0.85 (95% CI = 0.73-0.99) for overweight and 0.74 (95% CI = 0.57-0.96) for obesity. Underweight was a risk factor for higher mortality caused by infections (HR = 1.65 [95% CI = 1.13-2.40]). RR results corroborated primary HR results, with additionally lower infection-related mortality in overweight and obese than in normal-weight individuals. Like in the general population, underweight is a risk factor for mortality in old nursing home residents. However, uniquely, not only overweight but also obesity is protective, which has relevant nutritional goal implications in this population/setting.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Delgadez / Índice de Masa Corporal / Anciano Frágil / Sobrepeso / Hogares para Ancianos / Casas de Salud Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Obes Rev Asunto de la revista: METABOLISMO Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Delgadez / Índice de Masa Corporal / Anciano Frágil / Sobrepeso / Hogares para Ancianos / Casas de Salud Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Obes Rev Asunto de la revista: METABOLISMO Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido