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Changing Trends in Treatment of Acute Mania: Experience of a Tertiary Centre Over a Decade.
Arikan, Mehmet Kemal; Poyraz, Cana Aksoy; Bas, Alper; Saglam, N Gamze Usta; Batun, Gizem Cetiner; Gültekin, Gözde; Poyraz, Burç Çagri.
Afiliación
  • Arikan MK; Department of Psychiatry, Cerrahpasa Faculty of Medicine, Cerrahpasa Medical School, Istanbul University, Halaskargazi c. No:81 Çiçek apt. daire:8, Istanbul, Turkey.
  • Poyraz CA; Department of Psychiatry, Cerrahpasa Faculty of Medicine, Cerrahpasa Medical School, Istanbul University, Halaskargazi c. No:81 Çiçek apt. daire:8, Istanbul, Turkey. canaaksoy@yahoo.com.
  • Bas A; Department of Psychiatry, Cerrahpasa Faculty of Medicine, Cerrahpasa Medical School, Istanbul University, Halaskargazi c. No:81 Çiçek apt. daire:8, Istanbul, Turkey.
  • Saglam NG; Department of Psychiatry, Cerrahpasa Faculty of Medicine, Cerrahpasa Medical School, Istanbul University, Halaskargazi c. No:81 Çiçek apt. daire:8, Istanbul, Turkey.
  • Batun GC; Department of Psychiatry, Cerrahpasa Faculty of Medicine, Cerrahpasa Medical School, Istanbul University, Halaskargazi c. No:81 Çiçek apt. daire:8, Istanbul, Turkey.
  • Gültekin G; Department of Psychiatry, Cerrahpasa Faculty of Medicine, Cerrahpasa Medical School, Istanbul University, Halaskargazi c. No:81 Çiçek apt. daire:8, Istanbul, Turkey.
  • Poyraz BÇ; Department of Psychiatry, Cerrahpasa Faculty of Medicine, Cerrahpasa Medical School, Istanbul University, Halaskargazi c. No:81 Çiçek apt. daire:8, Istanbul, Turkey.
Psychiatr Q ; 87(2): 305-13, 2016 Jun.
Article en En | MEDLINE | ID: mdl-26220636
We investigated trends over a decade in the prescription of lithium, antiepileptics, and antipsychotic agents at discharge for patients hospitalised for acute mania. We conducted a retrospective review of medical records for 165 inpatients with acute mania who had been hospitalised in Cerrahpasa Faculty of Medicine, Department of Psychiatry during 2001-2002 and 2011-2012. Among 165 patients, prescription of olanzapine at discharge increased from 3 to 46 % (p < 0.001), while prescription of haloperidol decreased from 55 to 21 % (p < 0.001). Use of other atypical antipsychotics did not change significantly (risperidone decreased from 14 to 11 %, p = 0.5; quetiapine increased from 10 to 16 %, p = 0.2). Use of valproate, carbamazepine, and lithium did not change significantly. Use of electroconvulsive therapy in acute mania decreased by half from 27 to 13 % (p = 0.02). Typical antipsychotics alone or in combination with antiepileptics were the most common treatment regimen at discharge at 2001-2002; while 10 years later, they had been largely replaced by lithium or antiepileptics combined with second generation antipsychotics. Antipsychotic agents remained to be an important component of acute treatment of mania in our practice.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Bipolar / Quimioterapia Combinada / Utilización de Medicamentos / Terapia Electroconvulsiva Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Psychiatr Q Año: 2016 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Bipolar / Quimioterapia Combinada / Utilización de Medicamentos / Terapia Electroconvulsiva Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Psychiatr Q Año: 2016 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos