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Resveratrol: A Focus on Several Neurodegenerative Diseases.
Tellone, Ester; Galtieri, Antonio; Russo, Annamaria; Giardina, Bruno; Ficarra, Silvana.
Afiliación
  • Tellone E; Department of Chemical Sciences, University of Messina, V. le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
  • Galtieri A; Department of Chemical Sciences, University of Messina, V. le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
  • Russo A; Department of Chemical Sciences, University of Messina, V. le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
  • Giardina B; Biochemistry and Clinical Biochemistry Institute, School of Medicine, Catholic University, L. go F. Vito n.1, 00168 Rome, Italy ; C.N.R. Institute of Chemistry of Molecular Recognition, L. go F. Vito n.1, 00168 Rome, Italy.
  • Ficarra S; Department of Chemical Sciences, University of Messina, V. le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Oxid Med Cell Longev ; 2015: 392169, 2015.
Article en En | MEDLINE | ID: mdl-26180587
Molecules of the plant world are proving their effectiveness in countering, slowing down, and regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene structure has been proven to be a universal panacea, especially for a wide range of neurodegenerative diseases. This paper evaluates (in vivo and in vitro) the various molecular targets of this peculiar polyphenol and its ability to effectively counter several neurodegenerative disorders such as Parkinson's, Alzheimer's, and Huntington's diseases and amyotrophic lateral sclerosis. What emerges is that, in the deep heterogeneity of the pathologies evaluated, resveratrol through a convergence on the protein targets is able to give therapeutic responses in neuronal cells deeply diversified not only in morphological structure but especially in their function performed in the anatomical district to which they belong.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estilbenos / Enfermedades Neurodegenerativas Límite: Humans Idioma: En Revista: Oxid Med Cell Longev Asunto de la revista: METABOLISMO Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estilbenos / Enfermedades Neurodegenerativas Límite: Humans Idioma: En Revista: Oxid Med Cell Longev Asunto de la revista: METABOLISMO Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos