Stabilising lamellar stacks of lipid bilayers with soft confinement and steric effects.
Eur Phys J E Soft Matter
; 38(7): 78, 2015 Jul.
Article
en En
| MEDLINE
| ID: mdl-26174430
Structure and interactions stabilising the lamellar stack of mixed lipid bilayers in their fluid state are investigated by means of small-angle X-ray scattering. The (electrically neutral) bilayers are composed of a mixtures of lecithin, a zwitterionic phospholipid, and Simulsol, a non-ionic cosurfactant with an ethoxylated polar head. The soft confinement of the bilayer hydrophilic components is varied by changing hydration and bilayer composition, as well as the length of the cosurfactant polar head. Structural transitions are observed at low hydration, in the stacking order for the longer cosurfactant, and in the mixed bilayers for the shorter one. At higher hydration, the swelling of the lamellar stacks occurs with a significant, but continuous evolution in the mixed bilayer structure. The bilayer structural changes are discussed in analogy with the so-called "brush-to-mushroom" transition induced by lateral confinement, relevant for long linear polymers grafted onto rigid surfaces, taking also into account the role of vertical confinement.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Eur Phys J E Soft Matter
Asunto de la revista:
BIOFISICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Francia