Modifications of the mouse bone marrow microenvironment favor angiogenesis and correlate with disease progression from asymptomatic to symptomatic multiple myeloma.

Calcinotto, Arianna; Ponzoni, Maurilio; Ria, Roberto; Grioni, Matteo; Cattaneo, Elena; Villa, Isabella; Sabrina Bertilaccio, Maria Teresa; Chesi, Marta; Rubinacci, Alessandro; Tonon, Giovanni; Bergsagel, P Leif; Vacca, Angelo; Bellone, Matteo

Calcinotto, Arianna; Ponzoni, Maurilio; Ria, Roberto; Grioni, Matteo; Cattaneo, Elena; Villa, Isabella; Sabrina Bertilaccio, Maria Teresa; Chesi, Marta; Rubinacci, Alessandro; Tonon, Giovanni; Bergsagel, P Leif; Vacca, Angelo; Bellone, Matteo.

Afiliación

Calcinotto A; Cellular Immunology Unit; IRCCS San Raffaele Scientific Institute ; Milan, Italy ; Università Vita-Salute San Raffaele ; Milan, Italy.
Ponzoni M; Pathology and Myeloma Units; IRCCS San Raffaele Scientific Institute ; Milan, Italy.
Ria R; Department of Biomedical Sciences and Human Oncology; Internal Medicine and Clinical Oncology Unit; University of Bari Medical School ; Bari, Italy.
Grioni M; Cellular Immunology Unit; IRCCS San Raffaele Scientific Institute ; Milan, Italy.
Cattaneo E; Cellular Immunology Unit; IRCCS San Raffaele Scientific Institute ; Milan, Italy.
Villa I; Bone Metabolic Unit; Division of Cardiovascular Science; IRCCS San Raffaele Scientific Institute ; Milan, Italy.
Sabrina Bertilaccio MT; Division of Molecular Oncology; IRCCS San Raffaele Scientific Institute ; Milan, Italy.
Chesi M; Comprehensive Cancer Center; Mayo Clinic Arizona ; Scottsdale, AZ, USA.
Rubinacci A; Bone Metabolic Unit; Division of Cardiovascular Science; IRCCS San Raffaele Scientific Institute ; Milan, Italy.
Tonon G; Division of Molecular Oncology; IRCCS San Raffaele Scientific Institute ; Milan, Italy.
Bergsagel PL; Comprehensive Cancer Center; Mayo Clinic Arizona ; Scottsdale, AZ, USA.
Vacca A; Department of Biomedical Sciences and Human Oncology; Internal Medicine and Clinical Oncology Unit; University of Bari Medical School ; Bari, Italy.
Bellone M; Cellular Immunology Unit; IRCCS San Raffaele Scientific Institute ; Milan, Italy.

Oncoimmunology ; 4(6): e1008850, 2015 Jun.

Article en En | MEDLINE | ID: mdl-26155424

Palabras clave

BM, bone marrow; BMb, BM biopsies; M-spike, monoclonal (M) protein; MGUS, monoclonal gammopathy of undetermined significance; MM, multiple myeloma; MVD, microvessel density; SMM, smoldering multiple myeloma; T cells; TAMs, M2 tumor associated macrophages; TEMs, Tie2-expressing macrophages; angiogenesis; macrophages; multiple myeloma; smoldering multiple myeloma

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies Idioma: En Revista: Oncoimmunology Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

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