Investigations of the total flavonoids extracted from flowers of Abelmoschus manihot (L.) Medic against &#945;-naphthylisothiocyanate-induced cholestatic liver injury in rats.

Yan, Jia-Yin; Ai, Guo; Zhang, Xiao-Jian; Xu, Hai-Jiang; Huang, Zheng-Ming

Investigations of the total flavonoids extracted from flowers of Abelmoschus manihot (L.) Medic against α-naphthylisothiocyanate-induced cholestatic liver injury in rats.

Yan, Jia-Yin; Ai, Guo; Zhang, Xiao-Jian; Xu, Hai-Jiang; Huang, Zheng-Ming.

Afiliación

Yan JY; Department of Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Ai G; Institute of Aviation Medicine of Air Force, Beijing 100142, China; Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China. Electronic address: guoair@163.com.
Zhang XJ; Department of Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Xu HJ; Department of Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Huang ZM; Department of Pharmacy, 302 Hospital of PLA, Beijing 100039, China.

J Ethnopharmacol ; 172: 202-13, 2015 Aug 22.

Article en En | MEDLINE | ID: mdl-26133062

Asunto(s)

Abelmoschus/química; Colestasis/prevención & control; Flavonoides/farmacología; 1-Naftilisotiocianato/toxicidad; Administración Oral; Animales; Modelos Animales de Enfermedad; Relación Dosis-Respuesta a Droga; Medicamentos Herbarios Chinos/administración & dosificación; Medicamentos Herbarios Chinos/aislamiento & purificación; Medicamentos Herbarios Chinos/farmacología; Flavonoides/administración & dosificación; Flavonoides/aislamiento & purificación; Flores; Hígado/efectos de los fármacos; Hígado/patología; Masculino; Ratas; Ratas Wistar

Palabras clave

Abelmoschus manihot (L.) Medic; Cholestatic; Guercetin (PubChem CID: 5280343); Hepatoprotective; Hibifolin (PubChem CID: 5490334); Hyperin (PubChem CID: 5281643); Isoquercetin (PubChem CID: 5280804); Myricetin (PubChem CID: 5281672); Total flavonoids; α-Naphthylisothiocyanate

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavonoides / Colestasis / Abelmoschus Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Ethnopharmacol Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda

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