Evaluation of the Antitumor Efficacy of RNAi-Mediated Inhibition of CDC20 and Heparanase in an Orthotopic Liver Tumor Model.

Liu, Meizhou; Zhang, Yangde; Liao, Yunjun; Chen, Yixing; Pan, Yifeng; Tian, Hu; Zhan, Yongqiang; Liu, Dongjing

Liu, Meizhou; Zhang, Yangde; Liao, Yunjun; Chen, Yixing; Pan, Yifeng; Tian, Hu; Zhan, Yongqiang; Liu, Dongjing.

Afiliación

Liu M; 1 Hepatobiliary Enteric Surgery Research Center, Xiangya Hospital, Central South University , Changsha, People's Republic of China .
Zhang Y; 1 Hepatobiliary Enteric Surgery Research Center, Xiangya Hospital, Central South University , Changsha, People's Republic of China .
Liao Y; 2 Second People's Hospital of Shenzhen , Shenzhen, People's Republic of China .
Chen Y; 2 Second People's Hospital of Shenzhen , Shenzhen, People's Republic of China .
Pan Y; 1 Hepatobiliary Enteric Surgery Research Center, Xiangya Hospital, Central South University , Changsha, People's Republic of China .
Tian H; 3 Department of General Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University , Qianfoshan, People's Republic of China .
Zhan Y; 2 Second People's Hospital of Shenzhen , Shenzhen, People's Republic of China .
Liu D; 1 Hepatobiliary Enteric Surgery Research Center, Xiangya Hospital, Central South University , Changsha, People's Republic of China .

Cancer Biother Radiopharm ; 30(6): 233-9, 2015 Aug.

Article en En | MEDLINE | ID: mdl-26132704

Asunto(s)

Proteínas Cdc20/antagonistas & inhibidores; Proteínas Cdc20/metabolismo; Glucuronidasa/antagonistas & inhibidores; Glucuronidasa/metabolismo; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Interferencia de ARN/fisiología; Animales; Proteínas Cdc20/genética; Línea Celular Tumoral; Proliferación Celular; Modelos Animales de Enfermedad; Humanos; Neoplasias Hepáticas/patología; Masculino; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Transfección

Palabras clave

CDC20; RNA interference; animal model; heparanase; liver cancer

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interferencia de ARN / Proteínas Cdc20 / Glucuronidasa / Neoplasias Hepáticas Límite: Animals / Humans / Male Idioma: En Revista: Cancer Biother Radiopharm Asunto de la revista: FARMACIA / FARMACOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos

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