Identification and Characterization of a G Protein-binding Cluster in &#945;7 Nicotinic Acetylcholine Receptors.

King, Justin R; Nordman, Jacob C; Bridges, Samuel P; Lin, Ming-Kuan; Kabbani, Nadine

Identification and Characterization of a G Protein-binding Cluster in α7 Nicotinic Acetylcholine Receptors.

King, Justin R; Nordman, Jacob C; Bridges, Samuel P; Lin, Ming-Kuan; Kabbani, Nadine.

Afiliación

King JR; From the Department of Molecular Neuroscience, Krasnow Institute for Advanced Study and Department of Computer Science, George Mason University, Fairfax, Virginia 22030 and the INOVA Neuroscience Program, Annandale, Virginia 22003.
Nordman JC; From the Department of Molecular Neuroscience, Krasnow Institute for Advanced Study and Department of Computer Science, George Mason University, Fairfax, Virginia 22030 and the INOVA Neuroscience Program, Annandale, Virginia 22003.
Bridges SP; From the Department of Molecular Neuroscience, Krasnow Institute for Advanced Study and Department of Computer Science, George Mason University, Fairfax, Virginia 22030 and the INOVA Neuroscience Program, Annandale, Virginia 22003.
Lin MK; From the Department of Molecular Neuroscience, Krasnow Institute for Advanced Study and Department of Computer Science, George Mason University, Fairfax, Virginia 22030 and the INOVA Neuroscience Program, Annandale, Virginia 22003.
Kabbani N; From the Department of Molecular Neuroscience, Krasnow Institute for Advanced Study and Department of Computer Science, George Mason University, Fairfax, Virginia 22030 and the INOVA Neuroscience Program, Annandale, Virginia 22003 nkabbani@gmu.edu.

J Biol Chem ; 290(33): 20060-70, 2015 Aug 14.

Article en En | MEDLINE | ID: mdl-26088141

Asunto(s)

Proteínas de Unión al GTP/metabolismo; Receptor Nicotínico de Acetilcolina alfa 7/metabolismo; Secuencia de Aminoácidos; Animales; Sitios de Unión; Encéfalo/metabolismo; Ratones; Datos de Secuencia Molecular; Células PC12; Ratas; Homología de Secuencia de Aminoácido; Receptor Nicotínico de Acetilcolina alfa 7/química

Palabras clave

Cys loop receptor; G protein; binding motif; calcium intracellular release; choline; inositol 1,4,5-trisphosphate (IP3); nicotinic acetylcholine receptors (nAChR); phospholipase C

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Unión al GTP / Receptor Nicotínico de Acetilcolina alfa 7 Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos

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