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Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug Treatment.
Hoffman-Luca, C Gianna; Yang, Chao-Yie; Lu, Jianfeng; Ziazadeh, Daniel; McEachern, Donna; Debussche, Laurent; Wang, Shaomeng.
Afiliación
  • Hoffman-Luca CG; University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States of America; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Yang CY; University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States of America; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Lu J; University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States of America; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Ziazadeh D; University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States of America; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, United States of America.
  • McEachern D; University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States of America; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Debussche L; Sanofi Oncology, Vitry-sue-Seine, France.
  • Wang S; University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States of America; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, United States of America; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
PLoS One ; 10(6): e0128807, 2015.
Article en En | MEDLINE | ID: mdl-26070072
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Espiro / Osteosarcoma / Resistencia a Antineoplásicos / Proteínas Proto-Oncogénicas c-mdm2 / Indoles Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Espiro / Osteosarcoma / Resistencia a Antineoplásicos / Proteínas Proto-Oncogénicas c-mdm2 / Indoles Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos