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Flow diversion in vasculitic intracranial aneurysms? Repair of giant complex cavernous carotid aneurysm in polyarteritis nodosa using Pipeline embolization devices: first reported case.
Santos, Jaime Martinez; Kaderali, Zul; Spears, Julian; Rubin, Laurence A; Marotta, Thomas R.
Afiliación
  • Santos JM; Department of Neurosurgery, St Michael's Hospital, Toronto, Ontario, Canada.
  • Kaderali Z; Department of Diagnostic and Therapeutic Neuroradiology, St Michael's Hospital, Toronto, Ontario, Canada.
  • Spears J; Department of Neurosurgery, St Michael's Hospital, Toronto, Ontario, Canada.
  • Rubin LA; Department of Rheumatology, St Michael's Hospital, Toronto, Ontario, Canada.
  • Marotta TR; Department of Diagnostic and Therapeutic Neuroradiology, St Michael's Hospital, Toronto, Ontario, Canada.
BMJ Case Rep ; 20152015 May 29.
Article en En | MEDLINE | ID: mdl-26025975
Intracranial aneurysms in polyarteritis nodosa (PAN) are exceedingly rare lesions with unpredictable behavior that pose real challenges to microsurgical and endovascular interventions owing to their inflammatory nature. We introduce a safe and effective alternative for treating these aneurysms using Pipeline embolization devices (PEDs). A 20-year-old man presented with diplopia, headaches, chronic abdominal pain, and weight loss. Diagnostic evaluations confirmed PAN, including bilateral giant cavernous carotid aneurysms. Cyclophosphamide and steroids achieved significant and sustained clinical improvement, with a decision to follow the aneurysms serially. Seven years later the left unruptured aneurysm enlarged, causing a sudden severe headache and a cavernous sinus syndrome. Treatment of the symptomatic aneurysm was pursued using flow diversion (PED) and the internal carotid artery was successfully reconstructed with a total of four overlapping PEDs. At 6 months follow-up, complete exclusion of the aneurysm was demonstrated, with symptomatic recovery. This is the first description of using a flow-diverting technique in an inflammatory vasculitis. In this case, PEDs not only attained a definitive closure of the aneurysm but also reconstructed the damaged and fragile arterial segment affected with vasculitis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poliarteritis Nudosa / Arteria Carótida Interna / Aneurisma Intracraneal / Embolización Terapéutica Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: BMJ Case Rep Año: 2015 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poliarteritis Nudosa / Arteria Carótida Interna / Aneurisma Intracraneal / Embolización Terapéutica Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: BMJ Case Rep Año: 2015 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido