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Historical Matching Strategies in Kidney Paired Donation: The 7-Year Evolution of a Web-Based Virtual Matching System.
Fumo, D E; Kapoor, V; Reece, L J; Stepkowski, S M; Kopke, J E; Rees, S E; Smith, C; Roth, A E; Leichtman, A B; Rees, M A.
Afiliación
  • Fumo DE; The Alliance for Paired Donation, Maumee, OH.
  • Kapoor V; Department of Urology, University of Toledo Medical Center, Toledo, OH.
  • Reece LJ; Department of Urology, University of Toledo Medical Center, Toledo, OH.
  • Stepkowski SM; The Alliance for Paired Donation, Maumee, OH.
  • Kopke JE; The Alliance for Paired Donation, Maumee, OH.
  • Rees SE; Department of Urology, University of Toledo Medical Center, Toledo, OH.
  • Smith C; The Alliance for Paired Donation, Maumee, OH.
  • Roth AE; The Alliance for Paired Donation, Maumee, OH.
  • Leichtman AB; Department of Urology, University of Toledo Medical Center, Toledo, OH.
  • Rees MA; The Alliance for Paired Donation, Maumee, OH.
Am J Transplant ; 15(10): 2646-54, 2015 Oct.
Article en En | MEDLINE | ID: mdl-26015291
Failure to convert computer-identified possible kidney paired donation (KPD) exchanges into transplants has prohibited KPD from reaching its full potential. This study analyzes the progress of exchanges in moving from "offers" to completed transplants. Offers were divided into individual segments called 1-way transplants in order to calculate success rates. From 2007 to 2014, the Alliance for Paired Donation performed 243 transplants, 31 in collaboration with other KPD registries and 194 independently. Sixty-one of 194 independent transplants (31.4%) occurred via cycles, while the remaining 133 (68.6%) resulted from nonsimultaneous extended altruistic donor (NEAD) chains. Thirteen of 35 (37.1%) NEAD chains with at least three NEAD segments accounted for 68% of chain transplants (8.6 tx/chain). The "offer" and 1-way success rates were 21.9 and 15.5%, respectively. Three reasons for failure were found that could be prospectively prevented by changes in protocol or software: positive laboratory crossmatch (28%), transplant center declined donor (17%) and pair transplanted outside APD (14%). Performing a root cause analysis on failures in moving from offer to transplant has allowed the APD to improve protocols and software. These changes have improved the success rate and the number of transplants performed per year.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obtención de Tejidos y Órganos / Trasplante de Riñón / Internet Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obtención de Tejidos y Órganos / Trasplante de Riñón / Internet Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos