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Microbiological activity of ceftolozane/tazobactam, ceftazidime, meropenem, and piperacillin/tazobactam against Pseudomonas aeruginosa isolated from children with cystic fibrosis.
Kuti, Joseph L; Pettit, Rebecca S; Neu, Natalie; Cies, Jeffrey J; Lapin, Craig; Muhlebach, Marianne S; Novak, Kimberly J; Nguyen, Sean T; Saiman, Lisa; Nicolau, David P.
Afiliación
  • Kuti JL; Center for Anti-Infective Research & Development, Hartford Hospital, Hartford, CT, USA. Electronic address: joseph.kuti@hhchealth.org.
  • Pettit RS; Riley Hospital for Children, Indianapolis, IN, USA.
  • Neu N; Columbia University, New York, NY, USA.
  • Cies JJ; St Christopher's Hospital for Children, Philadelphia, PA, USA.
  • Lapin C; CT Children's Medical Center, Hartford, CT, USA.
  • Muhlebach MS; University of North Carolina, Chapel Hill, NC, USA.
  • Novak KJ; Nationwide Children's Hospital, Columbus, OH, USA.
  • Nguyen ST; Children's Medical Center, Dallas, TX, USA.
  • Saiman L; Columbia University, New York, NY, USA.
  • Nicolau DP; Center for Anti-Infective Research & Development, Hartford Hospital, Hartford, CT, USA.
Diagn Microbiol Infect Dis ; 83(1): 53-5, 2015 Sep.
Article en En | MEDLINE | ID: mdl-26003469
The activity of ceftolozane/tazobactam was tested against 50 nonduplicate Pseudomonas aeruginosa from 18 cystic fibrosis children collected in 2012-2014. These isolates were multidrug resistant with susceptibility to meropenem, ceftazidime, and piperacillin/tazobactam of 46%, 58%, and 50%, respectively. Ceftolozane/tazobactam was the most active with MIC50, MIC90, and percent susceptibility of 2mg/L, 8 mg/L, and 86%.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pseudomonas aeruginosa / Infecciones por Pseudomonas / Fibrosis Quística / Beta-Lactamas / Antibacterianos Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Diagn Microbiol Infect Dis Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pseudomonas aeruginosa / Infecciones por Pseudomonas / Fibrosis Quística / Beta-Lactamas / Antibacterianos Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Diagn Microbiol Infect Dis Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos