Your browser doesn't support javascript.
loading
Synthesis, spectral, thermal, fluorescence, antimicrobial, anthelmintic and DNA cleavage studies of mononuclear metal chelates of bi-dentate 2H-chromene-2-one Schiff base.
Prabhakara, Chetan T; Patil, Sangamesh A; Kulkarni, Ajaykumar D; Naik, Vinod H; Manjunatha, M; Kinnal, Shivshankar M; Badami, Prema S.
Afiliación
  • Prabhakara CT; P.G. Department of Chemistry, Karnatak University, Dharwad 580003, Karnataka, India.
  • Patil SA; P.G. Department of Chemistry, Karnatak University, Dharwad 580003, Karnataka, India. Electronic address: patil1956@rediffmail.com.
  • Kulkarni AD; Department of Chemistry, K.L.S. Gogte Institute of Technology, Belgaum 590008, Karnataka, India.
  • Naik VH; Department of Chemistry, V.D.R. Institute of Technology, Haliyal 581329, Karnataka, India.
  • Manjunatha M; Department of Chemistry, C.M.R. Institute of Technology, Bangalore 560037, Karnataka, India.
  • Kinnal SM; P.G. Department of Chemistry, Karnatak University, Dharwad 580003, Karnataka, India.
  • Badami PS; Department of Chemistry, Shri Sharanabasaveshwar College of Science, Gulbarga 585102, Karnataka, India.
J Photochem Photobiol B ; 148: 322-332, 2015 Jul.
Article en En | MEDLINE | ID: mdl-26002539
The Co(II), Ni(II) and Cu(II) complexes have been synthesized with Schiff base (HL), derived from 8-formyl-7-hydroxy-4-methylcoumarin with benzylamine. The Schiff base and its metal complexes were structurally characterized based on IR, (1)H NMR, (13)C NMR, UV-visible, ESR, magnetic, thermal, fluorescence, mass and ESI-MS studies. The complexes are completely soluble in DMF and DMSO. The molar conductance values indicate that, all synthesized metal complexes are non-electrolytic in nature. Elemental analysis reveals [ML2(H2O)2] stoichiometry, here MCo(II), Ni(II) and Cu(II), L=deprotonated ligand. The coordination between metal ion and Schiff base was supported by IR data, through deprotonation of phenolic oxygen of coumarin and azomethine nitrogen atoms. Solution electronic spectral results unveiled that all the synthesized complexes posses six coordinated geometry around metal ion. Thermal studies suggest the presence of coordinated water molecules. The Schiff base and its metal complexes have been screened for their antibacterial (Escherichia coli, Pseudomonas aureginosa, Klebsiella pneumoniae and Staphylococcus aureus) and antifungal (Penicillium chrysogenum and Aspergillus niger), anthelmintic (Pheretima posthuma) and DNA cleavage (Calf Thymus DNA) activities.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bases de Schiff / ADN / Complejos de Coordinación / Antihelmínticos / Antiinfecciosos Límite: Animals Idioma: En Revista: J Photochem Photobiol B Asunto de la revista: BIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: India Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bases de Schiff / ADN / Complejos de Coordinación / Antihelmínticos / Antiinfecciosos Límite: Animals Idioma: En Revista: J Photochem Photobiol B Asunto de la revista: BIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: India Pais de publicación: Suiza