Your browser doesn't support javascript.
loading
Electrodiagnosis and muscle biopsy in asymptomatic hyperckemia.
Kokotis, P; Papadimas, G K; Zouvelou, V; Zambelis, T; Manta, P; Karandreas, N.
Afiliación
  • Kokotis P; a Department of Neurology, School of Medicine, Eginition Hospital , University of Athens , Athens , Greece.
  • Papadimas GK; a Department of Neurology, School of Medicine, Eginition Hospital , University of Athens , Athens , Greece.
  • Zouvelou V; a Department of Neurology, School of Medicine, Eginition Hospital , University of Athens , Athens , Greece.
  • Zambelis T; a Department of Neurology, School of Medicine, Eginition Hospital , University of Athens , Athens , Greece.
  • Manta P; a Department of Neurology, School of Medicine, Eginition Hospital , University of Athens , Athens , Greece.
  • Karandreas N; a Department of Neurology, School of Medicine, Eginition Hospital , University of Athens , Athens , Greece.
Int J Neurosci ; 126(6): 514-519, 2016 Jun.
Article en En | MEDLINE | ID: mdl-26000931
Purpose/aim of the study: An increased serum level of creatine kinase (CK) in asymptomatic individuals is a diagnostic challenge, as it may be associated with either physiological conditions, such as exercise or even signal an ominous neuromuscular disease at a presymptomatic stage. The electromyogram (EMG) and the muscle biopsy play a key role in the evaluation of asymptomatic hyperckemia. The objective of this study was to investigate asymptomatic individuals with increased CK levels. MATERIALS AND METHODS: We comparatively studied EMG, quantitative EMG and muscle biopsy in asymptomatic clinically normal individuals with repeatedly increased CK levels. RESULTS: Conventional EMG was abnormal in 76% of patients, while quantitative EMG showed abnormal results in 88.9%. Muscle biopsy was diagnostic in 28%, one patient had neurogenic findings, 40% showed non-specific changes and 28% had normal results. CONCLUSIONS: EMG and especially quantitative EMG are highly sensitive in detecting subclinical neuromuscular diseases, whereas muscle biopsy may better contribute in the final diagnosis. No strong correlations were found between histological abnormalities and electrophysiological data, but further research is needed.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Neurosci Año: 2016 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Neurosci Año: 2016 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido