Rasagiline and rapid symptomatic motor effect in Parkinson's disease: review of literature.

Pistacchi, Michele; Martinello, Francesco; Gioulis, Manuela; Zambito Marsala, Sandro

Pistacchi, Michele; Martinello, Francesco; Gioulis, Manuela; Zambito Marsala, Sandro.

Afiliación

Pistacchi M; Department of Neurology, Santorso Hospital, Vicenza, Italy.
Martinello F; Rehabilitation Hospital of High Specialization, Neurology and Neurophysiology, Motta di Livenza (TV), Italy.
Gioulis M; Department of Neurology, San Martino Hospital, Belluno, Italy.
Zambito Marsala S; Department of Neurology, San Martino Hospital, Belluno, Italy.

Neurol Ther ; 3(1): 41-66, 2014 Jun.

Article en En | MEDLINE | ID: mdl-26000219

RESUMEN

Rasagiline is a monoamine oxidase type-B inhibitor used as monotherapy or in addition to levodopa in the treatment of Parkinson's disease. Once daily administration of rasagiline makes it easy to use, and allows good compliance by patients and adherence to therapy. Several multicenter studies have noted the effectiveness of rasagiline on both motor and non-motor symptoms, which require a complex pharmacologic approach, such as cognitive disorders. A recent study also reported a rapid action of rasagiline on motor symptoms. Positive findings have been highlighted by an economic model study. This review analyzes the main studies of rasagiline, with particular attention to the effectiveness of the drug on motor symptoms.

Palabras clave

Monoamine oxidase type-B inhibitor; Motor symptoms; Neurology; Parkinson's disease; Rasagiline

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies Idioma: En Revista: Neurol Ther Año: 2014 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Nueva Zelanda

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