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Multiple sessions of transcranial direct current stimulation and upper extremity rehabilitation in stroke: A review and meta-analysis.
Tedesco Triccas, L; Burridge, J H; Hughes, A M; Pickering, R M; Desikan, M; Rothwell, J C; Verheyden, G.
Afiliación
  • Tedesco Triccas L; Faculty of Health Sciences, University of Southampton, UK. Electronic address: l.tedesco-triccas@uea.ac.uk.
  • Burridge JH; Faculty of Health Sciences, University of Southampton, UK.
  • Hughes AM; Faculty of Health Sciences, University of Southampton, UK.
  • Pickering RM; Medical Statistics Group, Faculty of Medicine, University of Southampton, UK.
  • Desikan M; Sobell Department of Motor Neuroscience, Institute of Neurology, University College of London, UK.
  • Rothwell JC; Sobell Department of Motor Neuroscience, Institute of Neurology, University College of London, UK.
  • Verheyden G; KU Leuven, Department of Rehabilitation Sciences, Belgium.
Clin Neurophysiol ; 127(1): 946-955, 2016 Jan.
Article en En | MEDLINE | ID: mdl-25998205
OBJECTIVE: To systematically review the methodology in particular treatment options and outcomes and the effect of multiple sessions of transcranial direct current stimulation (tDCS) with rehabilitation programmes for upper extremity recovery post stroke. METHODS: A search was conducted for randomised controlled trials involving tDCS and rehabilitation for the upper extremity in stroke. Quality of included studies was analysed using the Modified Downs and Black form. The extent of, and effect of variation in treatment parameters such as anodal, cathodal and bi-hemispheric tDCS on upper extremity outcome measures of impairment and activity were analysed using meta-analysis. RESULTS: Nine studies (371 participants with acute, sub-acute and chronic stroke) were included. Different methodologies of tDCS and upper extremity intervention, outcome measures and timing of assessments were identified. Real tDCS combined with rehabilitation had a small non-significant effect of +0.11 (p=0.44) and +0.24 (p=0.11) on upper extremity impairments and activities at post-intervention respectively. CONCLUSION: Various tDCS methods have been used in stroke rehabilitation. The evidence so far is not statistically significant, but is suggestive of, at best, a small beneficial effect on upper extremity impairment. SIGNIFICANCE: Future research should focus on which patients and rehabilitation programmes are likely to respond to different tDCS regimes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Accidente Cerebrovascular / Extremidad Superior / Estimulación Transcraneal de Corriente Directa / Rehabilitación de Accidente Cerebrovascular Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Clin Neurophysiol Asunto de la revista: NEUROLOGIA / PSICOFISIOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Accidente Cerebrovascular / Extremidad Superior / Estimulación Transcraneal de Corriente Directa / Rehabilitación de Accidente Cerebrovascular Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Clin Neurophysiol Asunto de la revista: NEUROLOGIA / PSICOFISIOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos