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Pseudorabies Virus Fast Axonal Transport Occurs by a pUS9-Independent Mechanism.
Daniel, Gina R; Sollars, Patricia J; Pickard, Gary E; Smith, Gregory A.
Afiliación
  • Daniel GR; Department of Microbiology-Immunology, Northwestern University, Chicago, Illinois, USA.
  • Sollars PJ; School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
  • Pickard GE; School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
  • Smith GA; Department of Microbiology-Immunology, Northwestern University, Chicago, Illinois, USA g-smith3@northwestern.edu.
J Virol ; 89(15): 8088-91, 2015 Aug.
Article en En | MEDLINE | ID: mdl-25995254
Reactivation from latency results in transmission of neurotropic herpesviruses from the nervous system to body surfaces, referred to as anterograde axonal trafficking. The virus-encoded protein pUS9 promotes axonal dissemination by sorting virus particles into axons, but whether it is also an effector of fast axonal transport within axons is unknown. To determine the role of pUS9 in anterograde trafficking, we analyzed the axonal transport of pseudorabies virus in the presence and absence of pUS9.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfoproteínas / Seudorrabia / Axones / Enfermedades de los Porcinos / Proteínas Virales / Herpesvirus Suido 1 / Lipoproteínas Límite: Animals Idioma: En Revista: J Virol Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfoproteínas / Seudorrabia / Axones / Enfermedades de los Porcinos / Proteínas Virales / Herpesvirus Suido 1 / Lipoproteínas Límite: Animals Idioma: En Revista: J Virol Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos