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[New opportunities in the diagnosis of ulcerative colitis].
Eksp Klin Gastroenterol ; (2): 35-9, 2015.
Article en Ru | MEDLINE | ID: mdl-25993871
PURPOSE OF THE STUDY: to analyze the expression of markers of apoptosis and proliferation in patients with ulcerative colitis. MATERIALS AND METHODS: in 80 patients with ulcerative colitis the analysis of expression of apoptosis marker BAX and proliferation marker Ki-67, as well as the cell cycle regulator p53 in biopsy materials of the mucous membrane of the colon was carried out. THE RESULTS: decreased cell proliferative activity and increase of the apoptosis rate depending on the severity, the localization of the inflammatory process and its endoscopic activity were registered.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Regulación de la Expresión Génica / Proteína p53 Supresora de Tumor / Apoptosis / Proteína X Asociada a bcl-2 Tipo de estudio: Diagnostic_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: Ru Revista: Eksp Klin Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: Rusia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Regulación de la Expresión Génica / Proteína p53 Supresora de Tumor / Apoptosis / Proteína X Asociada a bcl-2 Tipo de estudio: Diagnostic_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: Ru Revista: Eksp Klin Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: Rusia