Liquid chromatography-tandem mass spectrometry for the quantification of flurbiprofen in human plasma and its application in a study of bioequivalence.

Mei, Chenghan; Li, Bin; Yin, Qiangfeng; Jin, Jing; Xiong, Ting; He, Wenjuan; Gao, Xiujuan; Xu, Rong; Zhou, Piqi; Zheng, Heng; Chen, Hui

Mei, Chenghan; Li, Bin; Yin, Qiangfeng; Jin, Jing; Xiong, Ting; He, Wenjuan; Gao, Xiujuan; Xu, Rong; Zhou, Piqi; Zheng, Heng; Chen, Hui.

Afiliación

Mei C; Department of Pharmacology, Institute of Clinical Pharmacology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China. Electronic address: chenhuitjmu@163.com.
Li B; Department of Pharmacology, Institute of Clinical Pharmacology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China.
Yin Q; Institute of Clinical Pharmacy, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430022, PR China.
Jin J; Department of Pharmacology, Institute of Clinical Pharmacology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China.
Xiong T; Department of Pharmacology, Institute of Clinical Pharmacology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China.
He W; Department of Pharmacology, Institute of Clinical Pharmacology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China.
Gao X; Department of Pharmacology, Institute of Clinical Pharmacology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China.
Xu R; Department of Pharmacology, Institute of Clinical Pharmacology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China.
Zhou P; Institute of Clinical Pharmacy, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430022, PR China.
Zheng H; Department of Pharmacology, Institute of Clinical Pharmacology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China.
Chen H; Department of Pharmacology, Institute of Clinical Pharmacology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China; Institute of Clinical Pharmacy, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science & Technology, Wuhan

J Chromatogr B Analyt Technol Biomed Life Sci ; 993-994: 69-74, 2015 Jul 01.

Article en En | MEDLINE | ID: mdl-25988430

Asunto(s)

Antiinflamatorios no Esteroideos/sangre; Cromatografía Líquida de Alta Presión/métodos; Flurbiprofeno/sangre; Espectrometría de Masas en Tándem/métodos; Adulto; Antiinflamatorios no Esteroideos/farmacocinética; Flurbiprofeno/farmacocinética; Humanos; Masculino; Equivalencia Terapéutica

Palabras clave

Bioequivalence; Flurbiprofen; Human plasma; LC-MS/MS; Pharmacokinetics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antiinflamatorios no Esteroideos / Flurbiprofeno / Cromatografía Líquida de Alta Presión / Espectrometría de Masas en Tándem Tipo de estudio: Evaluation_studies Límite: Adult / Humans / Male Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2015 Tipo del documento: Article Pais de publicación: Países Bajos

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