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The Relationship between Thyroid Function and Depressive Symptoms-the FIN-D2D Population-Based Study.
Saltevo, Juha; Kautiainen, Hannu; Mäntyselkä, Pekka; Jula, Antti; Keinänen-Kiukaanniemi, Sirkka; Korpi-Hyövälti, Eeva; Oksa, Heikki; Saaristo, Timo; Vanhala, Mauno.
Afiliación
  • Saltevo J; Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland.
  • Kautiainen H; Unit of Primary Health Care, Helsinki University Central Hospital, Finland. ; Department of General Practice, University of Helsinki, Helsinki, Finland. ; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.
  • Mäntyselkä P; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland. ; Institute of Public Health and Clinical Nutrition, Primary Health Care, School of Medicine, University of Eastern Finland, Kuopio, Finland.
  • Jula A; National Institute for Health and Welfare, Turku, Finland.
  • Keinänen-Kiukaanniemi S; Center for Life Course Epidemiology Research, University of Oulu, Oulu, Finland. ; Unit of Primary Health Care, Oulu University Hospital, Oulu, Finland.
  • Korpi-Hyövälti E; Department of Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland.
  • Oksa H; Pirkanmaa Hospital District, Finland. ; Tampere University Hospital, Tampere, Finland.
  • Saaristo T; Pirkanmaa Hospital District, Finland.
  • Vanhala M; Unit of Family Practice, Central Finland Central Hospital, Jyväskylä, Finland. ; Primary Health Care Unit, University of Eastern Finland, Kuopio, Finland.
Clin Med Insights Endocrinol Diabetes ; 8: 29-33, 2015.
Article en En | MEDLINE | ID: mdl-25987853
The association between thyroid function and depression is controversial. Both conditions express many similar symptoms, but the studies done give conflicting results. This study draws on a random, population-based sample of 4500 subjects aged 45-75 years old from Finland. The basic clinical study was done in 2007 for 1396 men and 1500 women (64% participation rate). Thyroid stimulating hormone (TSH), free thyroxine (F-T4), and free triiodothyronine (F-T3) were measured in 2013 from frozen samples. The 21-item Beck Depression Inventory (BDI-21) was applied to assess depressive symptoms (score ≥10 points). The prevalence of depressive symptoms was 17.5% in women and 12.5% in men. In women, the mean levels of TSH, F-T4, and F-T3 without depressive symptoms vs. with the presence of depressive symptoms were 1.92/1.97 mU/L, 13.1/13.1 pmol/L, and 3.91/3.87 pmol/L (NS), respectively. In men, the levels were 1.87/1.94 mU/L, 13.5/13.7 pmol/L, and 4.18/4.12 pmol/L (NS), respectively. In multiple regression analysis, TSH had no relationship to BDI-21 total score. We found no association between depressive symptoms and thyroid values.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Risk_factors_studies Idioma: En Revista: Clin Med Insights Endocrinol Diabetes Año: 2015 Tipo del documento: Article País de afiliación: Finlandia Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Risk_factors_studies Idioma: En Revista: Clin Med Insights Endocrinol Diabetes Año: 2015 Tipo del documento: Article País de afiliación: Finlandia Pais de publicación: Estados Unidos