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Advances in strategies and methodologies in cancer immunotherapy.
Lam, Samuel S K; Zhou, Feifan; Hode, Tomas; Nordquist, Robert E; Alleruzzo, Luciano; Raker, Joseph; Chen, Wei R.
Afiliación
  • Lam SS; Immunophotonics Inc., 4320 Forest Park Ave. #303, St. Louis, MO 63108, USA.
  • Zhou F; Biophotonics Research Laboratory, Center for Interdisciplinary Biomedical Education and Research, University of Central Oklahoma, Edmond, OK 73034, USA.
  • Hode T; Immunophotonics Inc., 4320 Forest Park Ave. #303, St. Louis, MO 63108, USA.
  • Nordquist RE; Immunophotonics Inc., 4320 Forest Park Ave. #303, St. Louis, MO 63108, USA.
  • Alleruzzo L; Immunophotonics Inc., 4320 Forest Park Ave. #303, St. Louis, MO 63108, USA.
  • Raker J; Immunophotonics Inc., 4320 Forest Park Ave. #303, St. Louis, MO 63108, USA.
  • Chen WR; Biophotonics Research Laboratory, Center for Interdisciplinary Biomedical Education and Research, University of Central Oklahoma, Edmond, OK 73034, USA and Immunophotonics Inc., 4320 Forest Park Ave. #303, St. Louis, MO 63108, USA.
Discov Med ; 19(105): 293-301, 2015 Apr.
Article en En | MEDLINE | ID: mdl-25977192
Since the invention of Coley's toxin by William Coley in early 1900s, the path for cancer immunotherapy has been a convoluted one. Although still not considered standard of care, with the FDA approval of trastuzumab, Provenge and ipilimumab, the medical and scientific community has started to embrace the possibility that immunotherapy could be a new hope for cancer patients with otherwise untreatable metastatic diseases. This review aims to summarize the development of some major strategies in cancer immunotherapy, from the earliest peptide vaccine and transfer of tumor specific antibodies/T cells to the more recent dendritic cell (DC) vaccines, whole cell tumor vaccines, and checkpoint blockade therapy. Discussion of some major milestones and obstacles in the shaping of the field and the future perspectives is included. Photoimmunotherapy is also reviewed as an example of emerging new therapies combining phototherapy and immunotherapy.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoterapia / Neoplasias Límite: Animals / Humans Idioma: En Revista: Discov Med Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoterapia / Neoplasias Límite: Animals / Humans Idioma: En Revista: Discov Med Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos