Your browser doesn't support javascript.
loading
New Interview and Observation Measures of the Broader Autism Phenotype: Description of Strategy and Reliability Findings for the Interview Measures.
Parr, Jeremy R; De Jonge, Maretha V; Wallace, Simon; Pickles, Andrew; Rutter, Michael L; Le Couteur, Ann S; van Engeland, Herman; Wittemeyer, Kerstin; McConachie, Helen; Roge, Bernadette; Mantoulan, Carine; Pedersen, Lennart; Isager, Torben; Poustka, Fritz; Bolte, Sven; Bolton, Patrick; Weisblatt, Emma; Green, Jonathan; Papanikolaou, Katerina; Baird, Gillian; Bailey, Anthony J.
Afiliación
  • Parr JR; From University of Oxford Department of Psychiatry, UK.
  • De Jonge MV; Institutes of Neuroscience, and Health and Society, Newcastle University, UK.
  • Wallace S; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Pickles A; From University of Oxford Department of Psychiatry, UK.
  • Rutter ML; Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
  • Le Couteur AS; MRC Centre for Social, Genetic and Developmental Psychiatry, King's College London, UK.
  • van Engeland H; Institutes of Neuroscience, and Health and Society, Newcastle University, UK.
  • Wittemeyer K; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
  • McConachie H; From University of Oxford Department of Psychiatry, UK.
  • Roge B; Institutes of Neuroscience, and Health and Society, Newcastle University, UK.
  • Mantoulan C; Centre d'Etudes et de Recherches en Psychopathologie, Toulouse, France.
  • Pedersen L; Centre d'Etudes et de Recherches en Psychopathologie, Toulouse, France.
  • Isager T; Center for Autisme, Denmark.
  • Poustka F; Center for Autisme, Denmark.
  • Bolte S; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, J.W. Goethe University Frankfurt, Germany.
  • Bolton P; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, J.W. Goethe University Frankfurt, Germany.
  • Weisblatt E; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
  • Green J; Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
  • Papanikolaou K; Cambridge University and Department of General and Adolescent Paediatrics, Institute of Child Health, University College London, London, UK.
  • Baird G; Academic Department of Child Psychiatry, University of Manchester, Manchester, UK.
  • Bailey AJ; University Department of Child Psychiatry, Athens, Greece.
Autism Res ; 8(5): 522-33, 2015 Oct.
Article en En | MEDLINE | ID: mdl-25959701
Clinical genetic studies confirm the broader autism phenotype (BAP) in some relatives of individuals with autism, but there are few standardized assessment measures. We developed three BAP measures (informant interview, self-report interview, and impression of interviewee observational scale) and describe the development strategy and findings from the interviews. International Molecular Genetic Study of Autism Consortium data were collected from families containing at least two individuals with autism. Comparison of the informant and self-report interviews was restricted to samples in which the interviews were undertaken by different researchers from that site (251 UK informants, 119 from the Netherlands). Researchers produced vignettes that were rated blind by others. Retest reliability was assessed in 45 participants. Agreement between live scoring and vignette ratings was very high. Retest stability for the interviews was high. Factor analysis indicated a first factor comprising social-communication items and rigidity (but not other repetitive domain items), and a second factor comprised mainly of reading and spelling impairments. Whole scale Cronbach's alphas were high for both interviews. The correlation between interviews for factor 1 was moderate (adult items 0.50; childhood items 0.43); Kappa values for between-interview agreement on individual items were mainly low. The correlations between individual items and total score were moderate. The inclusion of several factor 2 items lowered the overall Cronbach's alpha for the total set. Both interview measures showed good reliability and substantial stability over time, but the findings were better for factor 1 than factor 2. We recommend factor 1 scores be used for characterising the BAP.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Autístico / Entrevista Psicológica Tipo de estudio: Diagnostic_studies / Qualitative_research Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Autism Res Asunto de la revista: PSIQUIATRIA / TRANSTORNOS MENTAIS Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Autístico / Entrevista Psicológica Tipo de estudio: Diagnostic_studies / Qualitative_research Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Autism Res Asunto de la revista: PSIQUIATRIA / TRANSTORNOS MENTAIS Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos