Natural killer T cell activation overcomes immunosuppression to enhance clearance of postsurgical breast cancer metastasis in mice.

Gebremeskel, Simon; Clattenburg, Daniel R; Slauenwhite, Drew; Lobert, Lynnea; Johnston, Brent

Gebremeskel, Simon; Clattenburg, Daniel R; Slauenwhite, Drew; Lobert, Lynnea; Johnston, Brent.

Afiliación

Gebremeskel S; Department of Microbiology & Immunology; Dalhousie University ; Halifax, Nova Scotia, Canada ; Beatrice Hunter Cancer Research Institute ; Halifax, Nova Scotia, Canada.
Clattenburg DR; Department of Microbiology & Immunology; Dalhousie University ; Halifax, Nova Scotia, Canada ; Beatrice Hunter Cancer Research Institute ; Halifax, Nova Scotia, Canada.
Slauenwhite D; Department of Microbiology & Immunology; Dalhousie University ; Halifax, Nova Scotia, Canada.
Lobert L; Department of Microbiology & Immunology; Dalhousie University ; Halifax, Nova Scotia, Canada ; Beatrice Hunter Cancer Research Institute ; Halifax, Nova Scotia, Canada.
Johnston B; Department of Microbiology & Immunology; Dalhousie University ; Halifax, Nova Scotia, Canada ; Department of Pediatrics; Dalhousie University ; Halifax, Nova Scotia, Canada ; Department of Pathology; Dalhousie University ; Halifax, Nova Scotia, Canada ; Beatrice Hunter Cancer Research Institute

Oncoimmunology ; 4(3): e995562, 2015 Mar.

Article en En | MEDLINE | ID: mdl-25949924

Palabras clave

dendritic cells; metastatic breast cancer; myeloid derived suppressor cells; natural killer T cells; tumor immunotherapy; α-GalCer, α-galacotosylceramide; ALT, alanine aminotransferase; DC, dendritic cell; FBS, fetal bovine serum; GM-CSF, granulocyte-macrophage colony-stimulating factor; IFNÎ³, interferon-Î³; IL, interleukin; i.p., intraperitoneal; i.v., intravenous; MDSC, myeloid derived suppressor cell; NK cell, natural killer cell; NKT cell, natural killer T cell; RPMI-1640, Roswell Park Memorial Institute medium-1640; TCR, T cell receptor; Th, T helper.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Oncoimmunology Año: 2015 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos

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