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Management of venous thromboembolism in patients with acute leukemia at high bleeding risk: a multi-center study.
Napolitano, Mariasanta; Valore, Luca; Malato, Alessandra; Saccullo, Giorgia; Vetro, Calogero; Mitra, Maria Enza; Fabbiano, Francesco; Mannina, Donato; Casuccio, Alessandra; Lucchesi, Alessandro; Del Principe, Maria Ilaria; Candoni, Anna; Di Raimondo, Francesco; Siragusa, Sergio.
Afiliación
  • Napolitano M; a Hematoloy Unit & Thrombosis and Hemostasis Reference Regional Center, University of Palermo , Palermo , Italy.
  • Valore L; a Hematoloy Unit & Thrombosis and Hemostasis Reference Regional Center, University of Palermo , Palermo , Italy.
  • Malato A; b Hematology Unit, General Hospital "Cervello" , Palermo , Italy.
  • Saccullo G; a Hematoloy Unit & Thrombosis and Hemostasis Reference Regional Center, University of Palermo , Palermo , Italy.
  • Vetro C; c Department of Clinical and Molecular BioMedicine Hematology Unit , University Hospital of Catania , Catania , Italy.
  • Mitra ME; a Hematoloy Unit & Thrombosis and Hemostasis Reference Regional Center, University of Palermo , Palermo , Italy.
  • Fabbiano F; b Hematology Unit, General Hospital "Cervello" , Palermo , Italy.
  • Mannina D; d Hematology Unit, "Papardo" General Hospital , Messina , Italy.
  • Casuccio A; e Department of Health Promotion Sciences and Mother Child Care , University of Palermo , Palermo , Italy.
  • Lucchesi A; f Hematology and Oncology Unit, Istituto Scientifico Romagnolo Per Lo Studio e La Cura Dei Tumori, IRCCS , Meldola , Italy.
  • Del Principe MI; g Hematology Unit, "Tor Vergata" University Hospital , Roma , Italy.
  • Candoni A; h Hematology Unit, Udine University Hospital , Udine , Italy.
  • Di Raimondo F; c Department of Clinical and Molecular BioMedicine Hematology Unit , University Hospital of Catania , Catania , Italy.
  • Siragusa S; a Hematoloy Unit & Thrombosis and Hemostasis Reference Regional Center, University of Palermo , Palermo , Italy.
Leuk Lymphoma ; 57(1): 116-9, 2016.
Article en En | MEDLINE | ID: mdl-25944377
In the last decades, evaluation of clinically relevant thrombotic complications in patients with acute leukemia (AL) has been poorly investigated. The authors performed a multi-center study to evaluate the management of symptomatic venous thromboembolism (VTE) in adult patients with AL. The intention was to find as clinically relevant the following: symptomatic Venous Thrombosis (VT) occurred in typical (lower limbs) and atypical (cerebral, upper limbs, abdominal, etc) sites with or without pulmonary embolism (PE). Over a population of 1461 patients with AL, 22 cases of symptomatic VTE were recorded in hospitalized patients with a mean age of 54.6 years. The absolute incidence of VTE was 1.5%. VTE occurred during chemotherapy in 17/22 (77.2%) cases, mainly (14/17, 82.3%) during the induction phase. Treatment of acute VTE was based on Low Molecular Weight Heparin (LMWH) at full dosage for the first month from diagnosis and reduced dosage (75%) for the following months.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia / Tromboembolia Venosa Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Leuk Lymphoma Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia / Tromboembolia Venosa Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Leuk Lymphoma Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos